A fragment of Calpain-1 cleaved α-Synuclein quantified in serum is upregulated in patients with Parkinson’s disease

A fragment of Calpain-1 cleaved α-Synuclein quantified in serum is upregulated in patients with Parkinson’s disease

Abstract Parkinson’s disease (PD) is a progressive neurodegenerative condition. One of the unmet medical needs in PD, are tools for better diagnosis, prognosis, and efficacy of treatment, which reflects the disease course of the individual patient. Alpha-Synuclein (α-Synuclein) is a hallmark of synu...

Full description

Saved in:
Bibliographic Details
Main Authors: Signe Holm Nielsen, Cecilie Møller Hausgaard, Meryem Benmarce, Morten Karsdal, Kim Henriksen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Biomarker
α-Synuclein
Calpain-1
Immunoassay
Parkinson's Disease
α-SYN-C
Online Access:https://doi.org/10.1038/s41598-025-92726-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items