A Case of Relapsing Polychondritis Initiating with Unexplained Fever
Relapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. Here, we describe a case of RP initially presenting with high fever. The patient was referred to our hospital for further examination of fever of unknown origin (FUO). On admission, the patient reported d...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/9462489 |
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| _version_ | 1832559848498135040 |
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| author | Kosuke Hirayama Nozomi Iwanaga Yasumori Izumi Satoshi Yoshimura Kazuhiro Kurohama Mai Yamashita Taichi Takahata Ryuta Oku Masahiro Ito Atsushi Kawakami Kiyoshi Migita |
| author_facet | Kosuke Hirayama Nozomi Iwanaga Yasumori Izumi Satoshi Yoshimura Kazuhiro Kurohama Mai Yamashita Taichi Takahata Ryuta Oku Masahiro Ito Atsushi Kawakami Kiyoshi Migita |
| author_sort | Kosuke Hirayama |
| collection | DOAJ |
| description | Relapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. Here, we describe a case of RP initially presenting with high fever. The patient was referred to our hospital for further examination of fever of unknown origin (FUO). On admission, the patient reported dry cough in addition to fever. On physical examination, her red, swollen ears were noted, attributed on histology to inflammation with auricular perichondritis. She was diagnosed with RP and treated with oral prednisone (50 mg/day); her fever and auricular inflammation resolved. The patient no longer reported cough and body temperature returned to normal and the elevated levels of C-reactive protein (CRP) were normalized. In this case, identification of the origin of fever was a challenge because of unspecific symptoms; however, awareness of the systemic manifestations of RP may lead to the prompt diagnosis and therapeutic intervention. |
| format | Article |
| id | doaj-art-a117289e3f314f78a9da4a94ad219034 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-a117289e3f314f78a9da4a94ad2190342025-02-03T01:29:08ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/94624899462489A Case of Relapsing Polychondritis Initiating with Unexplained FeverKosuke Hirayama0Nozomi Iwanaga1Yasumori Izumi2Satoshi Yoshimura3Kazuhiro Kurohama4Mai Yamashita5Taichi Takahata6Ryuta Oku7Masahiro Ito8Atsushi Kawakami9Kiyoshi Migita10Department of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of Ophthalmology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of Otolaryngology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanDepartment of Rheumatology, Nagasaki University Hospital, Sakamoto 1-7-1, Nagasaki 852-8501, JapanDepartment of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, JapanRelapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. Here, we describe a case of RP initially presenting with high fever. The patient was referred to our hospital for further examination of fever of unknown origin (FUO). On admission, the patient reported dry cough in addition to fever. On physical examination, her red, swollen ears were noted, attributed on histology to inflammation with auricular perichondritis. She was diagnosed with RP and treated with oral prednisone (50 mg/day); her fever and auricular inflammation resolved. The patient no longer reported cough and body temperature returned to normal and the elevated levels of C-reactive protein (CRP) were normalized. In this case, identification of the origin of fever was a challenge because of unspecific symptoms; however, awareness of the systemic manifestations of RP may lead to the prompt diagnosis and therapeutic intervention.http://dx.doi.org/10.1155/2016/9462489 |
| spellingShingle | Kosuke Hirayama Nozomi Iwanaga Yasumori Izumi Satoshi Yoshimura Kazuhiro Kurohama Mai Yamashita Taichi Takahata Ryuta Oku Masahiro Ito Atsushi Kawakami Kiyoshi Migita A Case of Relapsing Polychondritis Initiating with Unexplained Fever Case Reports in Medicine |
| title | A Case of Relapsing Polychondritis Initiating with Unexplained Fever |
| title_full | A Case of Relapsing Polychondritis Initiating with Unexplained Fever |
| title_fullStr | A Case of Relapsing Polychondritis Initiating with Unexplained Fever |
| title_full_unstemmed | A Case of Relapsing Polychondritis Initiating with Unexplained Fever |
| title_short | A Case of Relapsing Polychondritis Initiating with Unexplained Fever |
| title_sort | case of relapsing polychondritis initiating with unexplained fever |
| url | http://dx.doi.org/10.1155/2016/9462489 |
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