An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China
Pityriasis versicolor (PV) is a common clinical problem associated with Malassezia species (Malassezia spp.). Controversies remain regarding the specific species involved in the development of PV. This study analyzed the difference in Malassezia spp. distribution in lesional and nonlesional skin in...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/182596 |
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| author | Zhen Xie Yuping Ran Hao Zhang Min Zhang Huiying Wan Conghui Li |
| author_facet | Zhen Xie Yuping Ran Hao Zhang Min Zhang Huiying Wan Conghui Li |
| author_sort | Zhen Xie |
| collection | DOAJ |
| description | Pityriasis versicolor (PV) is a common clinical problem associated with Malassezia species (Malassezia spp.). Controversies remain regarding the specific species involved in the development of PV. This study analyzed the difference in Malassezia spp. distribution in lesional and nonlesional skin in Chinese PV patients. A paired design was applied. Lesional and nonlesional scales from 24 cases were collected; real-time fluorescence quantitative PCR was used to detect 10 different Malassezia spp. In lesional skin, the highest detection rates were for M. globosa (95.8%), M. restricta (91.7%), and M. sympodialis (50.0%). In nonlesional skin, the highest detection rates were for M. globosa (87.5%), M. restricta (79.2%), and M. dermatis (33.3%). A significant difference in the detection rate was only found for M. sympodialis (50.8% versus 20.8%, P=0.04). Compared with nonlesional skin, the amount of M. globosa, M. restricta, and M. sympodialis in lesional skin was significantly higher (3.8±1.3, 2.5±1.1, and 3.2±1.6 times higher, resp.). The results of this study do not indicate that M. globosa and M. restricta are directly correlated with PV development; however, M. sympodialis is more likely related to PV development in Chinese individuals. |
| format | Article |
| id | doaj-art-a10c7b271a424639b0db09020452aa71 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-a10c7b271a424639b0db09020452aa712025-02-03T01:21:52ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/182596182596An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, ChinaZhen Xie0Yuping Ran1Hao Zhang2Min Zhang3Huiying Wan4Conghui Li5Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510000, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, ChinaPityriasis versicolor (PV) is a common clinical problem associated with Malassezia species (Malassezia spp.). Controversies remain regarding the specific species involved in the development of PV. This study analyzed the difference in Malassezia spp. distribution in lesional and nonlesional skin in Chinese PV patients. A paired design was applied. Lesional and nonlesional scales from 24 cases were collected; real-time fluorescence quantitative PCR was used to detect 10 different Malassezia spp. In lesional skin, the highest detection rates were for M. globosa (95.8%), M. restricta (91.7%), and M. sympodialis (50.0%). In nonlesional skin, the highest detection rates were for M. globosa (87.5%), M. restricta (79.2%), and M. dermatis (33.3%). A significant difference in the detection rate was only found for M. sympodialis (50.8% versus 20.8%, P=0.04). Compared with nonlesional skin, the amount of M. globosa, M. restricta, and M. sympodialis in lesional skin was significantly higher (3.8±1.3, 2.5±1.1, and 3.2±1.6 times higher, resp.). The results of this study do not indicate that M. globosa and M. restricta are directly correlated with PV development; however, M. sympodialis is more likely related to PV development in Chinese individuals.http://dx.doi.org/10.1155/2014/182596 |
| spellingShingle | Zhen Xie Yuping Ran Hao Zhang Min Zhang Huiying Wan Conghui Li An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China The Scientific World Journal |
| title | An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China |
| title_full | An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China |
| title_fullStr | An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China |
| title_full_unstemmed | An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China |
| title_short | An Analysis of the Malassezia Species Distribution in the Skin of Patients with Pityriasis Versicolor in Chengdu, China |
| title_sort | analysis of the malassezia species distribution in the skin of patients with pityriasis versicolor in chengdu china |
| url | http://dx.doi.org/10.1155/2014/182596 |
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