Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal

Introduction. Patient’s knowledge and attitude towards their treatment avert stereotypical misconceptions about the disease and its treatment, as well as aid in attaining optimal adherence. This study investigated the knowledge, attitude, practice, and adherence of antiretroviral therapy (ART) clien...

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Main Authors: Sweta Shrestha, Subodh Chataut, Badri Kc, Khagendra Acharya, Sait Kumar Pradhan, Sunil Shrestha
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:AIDS Research and Treatment
Online Access:http://dx.doi.org/10.1155/2023/7292115
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author Sweta Shrestha
Subodh Chataut
Badri Kc
Khagendra Acharya
Sait Kumar Pradhan
Sunil Shrestha
author_facet Sweta Shrestha
Subodh Chataut
Badri Kc
Khagendra Acharya
Sait Kumar Pradhan
Sunil Shrestha
author_sort Sweta Shrestha
collection DOAJ
description Introduction. Patient’s knowledge and attitude towards their treatment avert stereotypical misconceptions about the disease and its treatment, as well as aid in attaining optimal adherence. This study investigated the knowledge, attitude, practice, and adherence of antiretroviral therapy (ART) clients in Nepal. Method. A cross-sectional study was conducted among 165 ART clients visiting five ART sites in the far western region and the capital city of Nepal. The convenience sampling method was employed, and the data were collected through interviews with ART clients using a validated questionnaire. Binary logistic regression was used to identify associated factors. Result. Approximately 80.7% had adequate knowledge and 55% had a positive attitude towards ART. Stigmatization was associated with ARV by only 4.2%. Half of the participants (50.3%) revealed that they had surreptitiously stored their ART medication, diverging from the recommended storage guidelines. A significant proportion of respondents (33.3%) chose to repackage the medication as a strategy to prevent unintended disclosure of their HIV status. Many (59.3%) believed that ART does not prolong life. Nevertheless, they advocated the regular use of ART rather than taking it only when the health deteriorates (81.8%). The majority (97.6%) were found to be adherent to their ART. There was a significant association of age with a level of knowledge and attitude (p<0.05). A significant association was also found between knowledge and attitude towards ART (p<0.05). None of the variables had a significant association with adherence (p>0.05). Conclusion. Overall, adequate knowledge was demonstrated, whereas efforts are still needed to improve the attitude of ART clients towards ART. A need for counseling regarding the storage practices of ART is needed. A focus on ensuring the perfect translation of adequate knowledge and a positive attitude to the practice of ART clients is essential. Whether adequate ART knowledge and attitude scores will lead to near-perfect ART adherence needs further investigation.
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spelling doaj-art-a109aab67a91429190a0bb2e7cddad672025-02-03T05:52:24ZengWileyAIDS Research and Treatment2090-12592023-01-01202310.1155/2023/7292115Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in NepalSweta Shrestha0Subodh Chataut1Badri Kc2Khagendra Acharya3Sait Kumar Pradhan4Sunil Shrestha5Department of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of Management Informatics and CommunicationDepartment of Clinical PhysiologySchool of PharmacyIntroduction. Patient’s knowledge and attitude towards their treatment avert stereotypical misconceptions about the disease and its treatment, as well as aid in attaining optimal adherence. This study investigated the knowledge, attitude, practice, and adherence of antiretroviral therapy (ART) clients in Nepal. Method. A cross-sectional study was conducted among 165 ART clients visiting five ART sites in the far western region and the capital city of Nepal. The convenience sampling method was employed, and the data were collected through interviews with ART clients using a validated questionnaire. Binary logistic regression was used to identify associated factors. Result. Approximately 80.7% had adequate knowledge and 55% had a positive attitude towards ART. Stigmatization was associated with ARV by only 4.2%. Half of the participants (50.3%) revealed that they had surreptitiously stored their ART medication, diverging from the recommended storage guidelines. A significant proportion of respondents (33.3%) chose to repackage the medication as a strategy to prevent unintended disclosure of their HIV status. Many (59.3%) believed that ART does not prolong life. Nevertheless, they advocated the regular use of ART rather than taking it only when the health deteriorates (81.8%). The majority (97.6%) were found to be adherent to their ART. There was a significant association of age with a level of knowledge and attitude (p<0.05). A significant association was also found between knowledge and attitude towards ART (p<0.05). None of the variables had a significant association with adherence (p>0.05). Conclusion. Overall, adequate knowledge was demonstrated, whereas efforts are still needed to improve the attitude of ART clients towards ART. A need for counseling regarding the storage practices of ART is needed. A focus on ensuring the perfect translation of adequate knowledge and a positive attitude to the practice of ART clients is essential. Whether adequate ART knowledge and attitude scores will lead to near-perfect ART adherence needs further investigation.http://dx.doi.org/10.1155/2023/7292115
spellingShingle Sweta Shrestha
Subodh Chataut
Badri Kc
Khagendra Acharya
Sait Kumar Pradhan
Sunil Shrestha
Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
AIDS Research and Treatment
title Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
title_full Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
title_fullStr Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
title_full_unstemmed Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
title_short Knowledge, Attitude, Practice, and Adherence to Antiretroviral Therapy among People Living with HIV in Nepal
title_sort knowledge attitude practice and adherence to antiretroviral therapy among people living with hiv in nepal
url http://dx.doi.org/10.1155/2023/7292115
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