Actin maintains synaptic transmission by restraining vesicle release probability

Summary: Despite decades of pharmacological studies, how the ubiquitous cytoskeletal actin regulates synaptic transmission remains poorly understood. We addressed this issue with a tissue-specific knockout of actin β-isoform or γ-isoform, combined with recordings of postsynaptic EPSCs, presynaptic c...

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Bibliographic Details
Main Authors: Xin-Sheng Wu, Zhen Zhang, Yinghui Jin, Afreen Mushtaheed, Ling-Gang Wu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225002603
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