Human Recombinant Interleukin-6 and Leukemia Inhibitory Factor Improve Inner Cell Mass Cell Number but Lack Cryoprotective Activities on In Vitro-Produced Bovine Blastocysts

Human Recombinant Interleukin-6 and Leukemia Inhibitory Factor Improve Inner Cell Mass Cell Number but Lack Cryoprotective Activities on In Vitro-Produced Bovine Blastocysts

This work explored whether supplementing recombinant human interleukin-6 (IL6), interleukin-11 (IL11), or leukemia inhibitory factor (LIF) improves IVP bovine embryo development, morphology, and cryosurvivability. Embryos were treated from day 5 to 8 post-fertilization with either the carrier only (...

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Bibliographic Details
Main Authors: Mary A. Oliver, Kayla J. Alward, Michelle L. Rhoads, Alan D. Ealy
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Animals
Subjects:
cow
embryo
blastocyst
cytokine
cryopreservation
in vitro embryo production
Online Access:https://www.mdpi.com/2076-2615/15/5/668
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