Methylation risk score of C-reactive protein associates sleep health with related health outcomes

Methylation risk score of C-reactive protein associates sleep health with related health outcomes

Abstract C-reactive protein (CRP) reflects inflammation status and is linked to poor sleep, metabolic and cardiovascular health. Methylation (MRS) and polygenic risk scores (PRS) reflect long-term systemic inflammation, and genetically-determined CRP, respectively. To refine understanding of inflamm...

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Main Authors: Ziqing Wang, Danielle A. Wallace, Brian W. Spitzer, Tianyi Huang, Kent D. Taylor, Jerome I. Rotter, Stephen S. Rich, Peter Y. Liu, Martha L. Daviglus, Lifang Hou, Alberto R. Ramos, Sonya Kaur, J. Peter Durda, Hector M. González, Myriam Fornage, Susan Redline, Carmen R. Isasi, Tamar Sofer
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08226-1
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