Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against <i>Cryptococcus neoformans</i> H99

Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against <i>Cryptococcus neoformans</i> H99

<b>Background/Objectives:</b> Cryptococcosis, caused by <i>Cryptococcus neoformans</i> and <i>Cryptococcus gattii</i> species complexes, remains a significant health concern, particularly among immunocompromised patients. The emergence of antifungal resistance and...

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Main Authors: Naira Sulany Oliveira de Sousa, Juan Diego Ribeiro de Almeida, Linnek Silva da Rocha, Izabela de Mesquita Bárcia Moreira, Flávia da Silva Fernandes, Ani Beatriz Jackisch Matsuura, Kátia Santana Cruz, Emersom Silva Lima, Érica Simplício de Souza, Hagen Frickmann, João Vicente Braga de Souza
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antibiotics
Subjects:
<i>Cryptococcus</i>
naphthoquinones
amphotericin B
antifungal synergy
Online Access:https://www.mdpi.com/2079-6382/14/6/602
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