New chemometrics-assisted spectrophotometric methods for simultaneous determination of co-formulated drugs montelukast, rupatadine, and desloratadine in their different dosage combinations

New chemometrics-assisted spectrophotometric methods for simultaneous determination of co-formulated drugs montelukast, rupatadine, and desloratadine in their different dosage combinations

Abstract Two accurate, precise and robust multivariate chemometric methods were developed for the simultaneous determination of montelukast sodium (MON), rupatadine fumarate (RUP) and desloratadine (DES). These methods provide a cost-effective alternative to chromatographic techniques by utilizing s...

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Bibliographic Details
Main Authors: Marco M. Z. Sharkawi, Nehal F. Farid, Moataz H. Hassan, Said A. Hassan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Chemistry
Subjects:
Artificial neural network
Desloratadine
Genetic Algorithm
Montelukast
Rupatadine
Partial least squares
Online Access:https://doi.org/10.1186/s13065-024-01345-6
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