Annotation-free deep learning algorithm trained on hematoxylin & eosin images predicts epithelial-to-mesenchymal transition phenotype and endocrine response in estrogen receptor-positive breast cancer
Abstract Recent evidence indicates that endocrine resistance in estrogen receptor-positive (ER+) breast cancer is closely correlated with phenotypic characteristics of epithelial-to-mesenchymal transition (EMT). Nonetheless, identifying tumor tissues with a mesenchymal phenotype remains challenging...
Saved in:
| Main Authors: | Kaimin Hu, Yinan Wu, Yajing Huang, Meiqi Zhou, Yanyan Wang, Xingru Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | Breast Cancer Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13058-025-01959-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Interference of estrogen signaling by endocrine disruptors in male and female cells: Potential implications of BPS and PFOS in human development
by: Giulia Gaggi, et al.
Published: (2025-09-01) -
Intercellular communication between extracellular vesicles from conditioned macrophages and breast cancer cells drives endocrine therapy resistance
by: María C. Rodriguez-Baili, et al.
Published: (2025-06-01) -
Estrogen receptor alpha dynamics and plasticity during endocrine resistance
by: Aswathy Sivasailam, et al.
Published: (2025-06-01) -
Alliin Induces Reconstitution of Testes Damaged by Estrogen Overstimulation by Regulating Apoptosis
by: Dae-Seung Kim, et al.
Published: (2024-11-01) -
Teleost fish metamorphosis under the influence of estrogenic hormones: targeting the thyroid axis – a literature review
by: Nathalie Leroux, et al.
Published: (2025-07-01)