Taraxacum sinicum Kitag. (Binpu-3) root extract inhibits tumor invasion via Notch signaling in Drosophila and human breast cancer MDA-MB-231 cells

Taraxacum sinicum Kitag. (Binpu-3) root extract inhibits tumor invasion via Notch signaling in Drosophila and human breast cancer MDA-MB-231 cells

Metastasis is the primary cause of death in patients with malignant tumors. Therefore, effectively controlling or reversing tumor cell growth and metastasis is crucial for treating malignant tumors. In this study, we investigated the effects and underlying mechanisms of Binpu-3 (a strain of Taraxacu...

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Bibliographic Details
Main Authors: Jiawei Wu, Jianbo Zhang, Wanyu Shu, Wei Feng, Ran Meng, Lingyu Kong, Huijuan Cao, Chunhua Jiang, Sitong Wang, Fanwu Wu, Chenxi Wu, Xiuping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Taraxacum sinicum Kitag.
root extract
tumor invasion
Notch
Drosophila
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1494545/full
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