Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein

Glycosylation is one of the most important posttranslational modifications for proteins, including therapeutic antibodies, and greatly influences protein physiochemical properties. In this study, glycopeptide mapping of a reference and biosimilar recombinant antibodies (rAbs) was performed using liq...

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Bibliographic Details
Main Authors: Young Hye Hahm, Sung Ho Hahm, Hyoun Young Jo, Yeong Hee Ahn
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2018/8605021
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