ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis
Kidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy. In a minor subset of cases, pauci-immune glomerulonephritis may be present. Most often, such patients wi...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2024/4181660 |
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| author | Camille Ng Angela Penney Rojin Sharaflari Akash Pathak John H. Howard III Kuang-Yu Jen |
| author_facet | Camille Ng Angela Penney Rojin Sharaflari Akash Pathak John H. Howard III Kuang-Yu Jen |
| author_sort | Camille Ng |
| collection | DOAJ |
| description | Kidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy. In a minor subset of cases, pauci-immune glomerulonephritis may be present. Most often, such patients will demonstrate the presence of antineutrophil cytoplasmic antibodies (ANCA) on serologic testing. A growing number of cases of ANCA-associated glomerulonephritis due to Bartonella endocarditis have been reported. This type of endocarditis can present diagnostic difficulties given that these patients are often culture negative. Herein, we report a challenging case of ANCA-negative pauci-immune glomerulonephritis showing florid crescents on biopsy that was associated with Bartonella endocarditis. |
| format | Article |
| id | doaj-art-a068af011c3844c09317c8dd07333368 |
| institution | Kabale University |
| issn | 2090-665X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-a068af011c3844c09317c8dd073333682025-02-03T10:56:49ZengWileyCase Reports in Nephrology2090-665X2024-01-01202410.1155/2024/4181660ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella EndocarditisCamille Ng0Angela Penney1Rojin Sharaflari2Akash Pathak3John H. Howard III4Kuang-Yu Jen5College of MedicineCollege of MedicineCollege of MedicineCollege of MedicineCapital Nephrology Medical GroupDepartment of Pathology and Laboratory MedicineKidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy. In a minor subset of cases, pauci-immune glomerulonephritis may be present. Most often, such patients will demonstrate the presence of antineutrophil cytoplasmic antibodies (ANCA) on serologic testing. A growing number of cases of ANCA-associated glomerulonephritis due to Bartonella endocarditis have been reported. This type of endocarditis can present diagnostic difficulties given that these patients are often culture negative. Herein, we report a challenging case of ANCA-negative pauci-immune glomerulonephritis showing florid crescents on biopsy that was associated with Bartonella endocarditis.http://dx.doi.org/10.1155/2024/4181660 |
| spellingShingle | Camille Ng Angela Penney Rojin Sharaflari Akash Pathak John H. Howard III Kuang-Yu Jen ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis Case Reports in Nephrology |
| title | ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis |
| title_full | ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis |
| title_fullStr | ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis |
| title_full_unstemmed | ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis |
| title_short | ANCA-Negative Pauci-Immune Glomerulonephritis Associated with Bartonella Endocarditis |
| title_sort | anca negative pauci immune glomerulonephritis associated with bartonella endocarditis |
| url | http://dx.doi.org/10.1155/2024/4181660 |
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