Biomarkers: A Definite Plus in Pneumonia

During the past few years, biomarkers have emerged as an indispensible tool in the diagnosis of pneumonia. To find an ideal diagnostic biomarker for pneumonia is not an easy task. Not only should it allow an early diagnosis of the condition, but it should also allow differential diagnosis from other...

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Main Authors: Hanssa Summah, Jie-Ming Qu
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2009/675753
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author Hanssa Summah
Jie-Ming Qu
author_facet Hanssa Summah
Jie-Ming Qu
author_sort Hanssa Summah
collection DOAJ
description During the past few years, biomarkers have emerged as an indispensible tool in the diagnosis of pneumonia. To find an ideal diagnostic biomarker for pneumonia is not an easy task. Not only should it allow an early diagnosis of the condition, but it should also allow differential diagnosis from other noninfectious conditions. Ongoing research is being done in this field so as to put an array of biomarkers at the disposal of doctors to improve the diagnosis of pneumonia when patients present to them with cough or nonspecific symptoms which could easily be misinterpreted as symptoms of other conditions. Procalcitonin and soluble triggering receptor expressed on myeloid cells-1 have emerged as reliable diagnostic markers in pneumonia, and are better when compared to other markers, namely, C-reactive protein, leukocyte count, and proinflammatory cytokines. Many other biomarkers are being studied for their probable use in diagnosing pneumonia but have yet to prove their benefit.
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spelling doaj-art-a0678a07245040faa165f97634b4d52a2025-02-03T01:00:37ZengWileyMediators of Inflammation0962-93511466-18612009-01-01200910.1155/2009/675753675753Biomarkers: A Definite Plus in PneumoniaHanssa Summah0Jie-Ming Qu1Department of Pulmonary Medicine, Huadong Hospital, Fudan University School of Medicine, Shanghai 200040, ChinaDepartment of Pulmonary Medicine, Huadong Hospital, Fudan University School of Medicine, Shanghai 200040, ChinaDuring the past few years, biomarkers have emerged as an indispensible tool in the diagnosis of pneumonia. To find an ideal diagnostic biomarker for pneumonia is not an easy task. Not only should it allow an early diagnosis of the condition, but it should also allow differential diagnosis from other noninfectious conditions. Ongoing research is being done in this field so as to put an array of biomarkers at the disposal of doctors to improve the diagnosis of pneumonia when patients present to them with cough or nonspecific symptoms which could easily be misinterpreted as symptoms of other conditions. Procalcitonin and soluble triggering receptor expressed on myeloid cells-1 have emerged as reliable diagnostic markers in pneumonia, and are better when compared to other markers, namely, C-reactive protein, leukocyte count, and proinflammatory cytokines. Many other biomarkers are being studied for their probable use in diagnosing pneumonia but have yet to prove their benefit.http://dx.doi.org/10.1155/2009/675753
spellingShingle Hanssa Summah
Jie-Ming Qu
Biomarkers: A Definite Plus in Pneumonia
Mediators of Inflammation
title Biomarkers: A Definite Plus in Pneumonia
title_full Biomarkers: A Definite Plus in Pneumonia
title_fullStr Biomarkers: A Definite Plus in Pneumonia
title_full_unstemmed Biomarkers: A Definite Plus in Pneumonia
title_short Biomarkers: A Definite Plus in Pneumonia
title_sort biomarkers a definite plus in pneumonia
url http://dx.doi.org/10.1155/2009/675753
work_keys_str_mv AT hanssasummah biomarkersadefiniteplusinpneumonia
AT jiemingqu biomarkersadefiniteplusinpneumonia