Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia

Infantile fibrosarcoma (IF) is a rare malignant fibroblastic tumor that affects infants and young children, occurring most commonly in the extremities. Here, we present a 14-year-old patient with an abdominal mass incidentally detected after a blunt injury to the abdomen. The initial trauma protocol...

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Main Authors: Kamand Khalaj, Nikoo Fattahi, Allen C. Omo-Ogboi, Jaiyeola O. Thomas-Ogunniyi, Olanrewaju A. Ogunleye, Ashish Khanal, Larry A. Kramer
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2023/3178778
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author Kamand Khalaj
Nikoo Fattahi
Allen C. Omo-Ogboi
Jaiyeola O. Thomas-Ogunniyi
Olanrewaju A. Ogunleye
Ashish Khanal
Larry A. Kramer
author_facet Kamand Khalaj
Nikoo Fattahi
Allen C. Omo-Ogboi
Jaiyeola O. Thomas-Ogunniyi
Olanrewaju A. Ogunleye
Ashish Khanal
Larry A. Kramer
author_sort Kamand Khalaj
collection DOAJ
description Infantile fibrosarcoma (IF) is a rare malignant fibroblastic tumor that affects infants and young children, occurring most commonly in the extremities. Here, we present a 14-year-old patient with an abdominal mass incidentally detected after a blunt injury to the abdomen. The initial trauma protocol CT revealed a high attenuation mesenteric lesion in the left central abdomen suggestive of mesenteric hematoma. However, the possibility of a solid neoplastic mass lesion could not be excluded. Further evaluation with dynamic contrast-enhanced serial MRI showed a progressive enhancing mass and excluded a hyperacute hematoma with active bleeding. The mass was resected, and histopathological examination and molecular analysis of tumor cells were consistent with a high-grade fibrosarcoma with KMT2D : BCOR fusion.
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institution Kabale University
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publishDate 2023-01-01
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series Case Reports in Radiology
spelling doaj-art-a0659850fbb74bbc9f5a8fe11bfd8bd72025-02-03T06:47:29ZengWileyCase Reports in Radiology2090-68702023-01-01202310.1155/2023/3178778Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus NeoplasiaKamand Khalaj0Nikoo Fattahi1Allen C. Omo-Ogboi2Jaiyeola O. Thomas-Ogunniyi3Olanrewaju A. Ogunleye4Ashish Khanal5Larry A. Kramer6Department of Diagnostic and Interventional ImagingDepartment of Diagnostic and Interventional ImagingDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDepartment of Diagnostic and Interventional ImagingDepartment of Diagnostic and Interventional ImagingDepartment of Diagnostic and Interventional ImagingInfantile fibrosarcoma (IF) is a rare malignant fibroblastic tumor that affects infants and young children, occurring most commonly in the extremities. Here, we present a 14-year-old patient with an abdominal mass incidentally detected after a blunt injury to the abdomen. The initial trauma protocol CT revealed a high attenuation mesenteric lesion in the left central abdomen suggestive of mesenteric hematoma. However, the possibility of a solid neoplastic mass lesion could not be excluded. Further evaluation with dynamic contrast-enhanced serial MRI showed a progressive enhancing mass and excluded a hyperacute hematoma with active bleeding. The mass was resected, and histopathological examination and molecular analysis of tumor cells were consistent with a high-grade fibrosarcoma with KMT2D : BCOR fusion.http://dx.doi.org/10.1155/2023/3178778
spellingShingle Kamand Khalaj
Nikoo Fattahi
Allen C. Omo-Ogboi
Jaiyeola O. Thomas-Ogunniyi
Olanrewaju A. Ogunleye
Ashish Khanal
Larry A. Kramer
Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
Case Reports in Radiology
title Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
title_full Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
title_fullStr Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
title_full_unstemmed Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
title_short Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia
title_sort incidental detection of a rare pediatric high grade fibrosarcoma in a post traumatic setting the conundrum of intra abdominal hematoma versus neoplasia
url http://dx.doi.org/10.1155/2023/3178778
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