One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature

β-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has...

Full description

Saved in:
Bibliographic Details
Main Authors: Zahed Karimi-Jaberi, Korosh Mohammadi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/925617
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549812525858816
author Zahed Karimi-Jaberi
Korosh Mohammadi
author_facet Zahed Karimi-Jaberi
Korosh Mohammadi
author_sort Zahed Karimi-Jaberi
collection DOAJ
description β-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has been used as solid acid catalyst for the preparation of β-acetamido ketones. The remarkable advantages offered by this method are green catalyst, mild reaction conditions, simple procedure, short reaction times, and good-to-excellent yields of products.
format Article
id doaj-art-a0650b6462734817bad64f07f7991225
institution Kabale University
issn 1537-744X
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-a0650b6462734817bad64f07f79912252025-02-03T06:08:31ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/925617925617One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room TemperatureZahed Karimi-Jaberi0Korosh Mohammadi1Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117, Fars, Firoozabad, IranDepartment of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117, Fars, Firoozabad, Iranβ-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has been used as solid acid catalyst for the preparation of β-acetamido ketones. The remarkable advantages offered by this method are green catalyst, mild reaction conditions, simple procedure, short reaction times, and good-to-excellent yields of products.http://dx.doi.org/10.1100/2012/925617
spellingShingle Zahed Karimi-Jaberi
Korosh Mohammadi
One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
The Scientific World Journal
title One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
title_full One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
title_fullStr One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
title_full_unstemmed One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
title_short One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
title_sort one pot synthesis of β acetamido ketones using boric acid at room temperature
url http://dx.doi.org/10.1100/2012/925617
work_keys_str_mv AT zahedkarimijaberi onepotsynthesisofbacetamidoketonesusingboricacidatroomtemperature
AT koroshmohammadi onepotsynthesisofbacetamidoketonesusingboricacidatroomtemperature