One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature
β-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has...
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Language: | English |
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Wiley
2012-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/2012/925617 |
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author | Zahed Karimi-Jaberi Korosh Mohammadi |
author_facet | Zahed Karimi-Jaberi Korosh Mohammadi |
author_sort | Zahed Karimi-Jaberi |
collection | DOAJ |
description | β-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has been used as solid acid catalyst for the preparation of β-acetamido ketones. The remarkable advantages offered by this method are green catalyst, mild reaction conditions, simple procedure, short reaction times, and good-to-excellent yields of products. |
format | Article |
id | doaj-art-a0650b6462734817bad64f07f7991225 |
institution | Kabale University |
issn | 1537-744X |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-a0650b6462734817bad64f07f79912252025-02-03T06:08:31ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/925617925617One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room TemperatureZahed Karimi-Jaberi0Korosh Mohammadi1Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117, Fars, Firoozabad, IranDepartment of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117, Fars, Firoozabad, Iranβ-acetamido ketones were synthesized in excellent yields through one-pot condensation reaction of aldehydes, acetophenones, acetyl chloride, and acetonitrile in the presence of boric acid as a solid heterogeneous catalyst at room temperature. It is the first successful report of boric acid that has been used as solid acid catalyst for the preparation of β-acetamido ketones. The remarkable advantages offered by this method are green catalyst, mild reaction conditions, simple procedure, short reaction times, and good-to-excellent yields of products.http://dx.doi.org/10.1100/2012/925617 |
spellingShingle | Zahed Karimi-Jaberi Korosh Mohammadi One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature The Scientific World Journal |
title | One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature |
title_full | One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature |
title_fullStr | One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature |
title_full_unstemmed | One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature |
title_short | One-Pot Synthesis of β-Acetamido Ketones Using Boric Acid at Room Temperature |
title_sort | one pot synthesis of β acetamido ketones using boric acid at room temperature |
url | http://dx.doi.org/10.1100/2012/925617 |
work_keys_str_mv | AT zahedkarimijaberi onepotsynthesisofbacetamidoketonesusingboricacidatroomtemperature AT koroshmohammadi onepotsynthesisofbacetamidoketonesusingboricacidatroomtemperature |