Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane
Background: The preterm premature rupture of the membrane is linked to various perinatal problems, including chorioamnionitis. Objectives: To evaluate the use of serum ferritin, C-reactive protein, and procalcitonin as early indicators for predictions of subclinical intra-amniotic fluid infection...
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College of Medicine University of Baghdad
2024-12-01
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| Series: | مجلة كلية الطب |
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| Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1997 |
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| author | Balsam N. Nahedh Mahdi M. Shalal |
| author_facet | Balsam N. Nahedh Mahdi M. Shalal |
| author_sort | Balsam N. Nahedh |
| collection | DOAJ |
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Background: The preterm premature rupture of the membrane is linked to various perinatal problems, including chorioamnionitis.
Objectives: To evaluate the use of serum ferritin, C-reactive protein, and procalcitonin as early indicators for predictions of subclinical intra-amniotic fluid infection.
Methods: A case-control study was conducted at Baghdad Teaching Hospital from January to October 2021. A convenient sample of 90 singleton pregnant women with a live fetus between 24 - 36 weeks of gestation were divided into three groups: Group 1 (controls) included 30 women with intact membranes and no signs of labour seen in the outpatient obstetrics clinic in Baghdad Teaching Hospital; Group 2 included 30 women with preterm premature rupture of membrane (PPROM) but without chorioamnionitis; and Group 3 included 30 women with PPROM and chorioamnionitis. The second and third groups were collected from the labour room in Baghdad Teaching Hospital.
Results: There was no significant difference in the levels of C-reactive protein between the study groups. Serum ferritin and Procalcitonin levels were normal in all of the participants, with a significant difference in the level of Procalcitonin between group 2 (PPROM with chorioamnionitis) and group 3 (PPROM without chorioamnionitis).
Conclusion: Procalcitonin might be used to detect the presence of chorioamnionitis. Serum ferritin and C-reactive protein had no role in the detection of chorioamnionitis among patients with preterm premature membrane rupture.
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| format | Article |
| id | doaj-art-a0267be821764864af15a71ba367b884 |
| institution | Kabale University |
| issn | 0041-9419 2410-8057 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | College of Medicine University of Baghdad |
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| series | مجلة كلية الطب |
| spelling | doaj-art-a0267be821764864af15a71ba367b8842025-01-19T12:24:11ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572024-12-0166410.32007/jfacmedbagdad.6621997Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of MembraneBalsam N. Nahedh0https://orcid.org/0009-0006-1087-2250Mahdi M. Shalal1https://orcid.org/0000-0002-2221-6510Department of Obstetrics and Gynecology, Baghdad Teaching Hospital, Baghdad, Iraq.Department of Obstetrics and Gynecology, College of Medicine, University of Baghdad, Baghdad, Iraq. Background: The preterm premature rupture of the membrane is linked to various perinatal problems, including chorioamnionitis. Objectives: To evaluate the use of serum ferritin, C-reactive protein, and procalcitonin as early indicators for predictions of subclinical intra-amniotic fluid infection. Methods: A case-control study was conducted at Baghdad Teaching Hospital from January to October 2021. A convenient sample of 90 singleton pregnant women with a live fetus between 24 - 36 weeks of gestation were divided into three groups: Group 1 (controls) included 30 women with intact membranes and no signs of labour seen in the outpatient obstetrics clinic in Baghdad Teaching Hospital; Group 2 included 30 women with preterm premature rupture of membrane (PPROM) but without chorioamnionitis; and Group 3 included 30 women with PPROM and chorioamnionitis. The second and third groups were collected from the labour room in Baghdad Teaching Hospital. Results: There was no significant difference in the levels of C-reactive protein between the study groups. Serum ferritin and Procalcitonin levels were normal in all of the participants, with a significant difference in the level of Procalcitonin between group 2 (PPROM with chorioamnionitis) and group 3 (PPROM without chorioamnionitis). Conclusion: Procalcitonin might be used to detect the presence of chorioamnionitis. Serum ferritin and C-reactive protein had no role in the detection of chorioamnionitis among patients with preterm premature membrane rupture. https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1997C-reactive proteinChorioamnionitisPreterm premature rupture of membraneProcalcitoninSerum ferritin |
| spellingShingle | Balsam N. Nahedh Mahdi M. Shalal Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane مجلة كلية الطب C-reactive protein Chorioamnionitis Preterm premature rupture of membrane Procalcitonin Serum ferritin |
| title | Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane |
| title_full | Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane |
| title_fullStr | Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane |
| title_full_unstemmed | Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane |
| title_short | Maternal Serum Ferritin, C-Reactive Protein, and Procalcitonin Levels for Predicting Subclinical Intra-Amniotic Infection in Preterm Premature Rupture of Membrane |
| title_sort | maternal serum ferritin c reactive protein and procalcitonin levels for predicting subclinical intra amniotic infection in preterm premature rupture of membrane |
| topic | C-reactive protein Chorioamnionitis Preterm premature rupture of membrane Procalcitonin Serum ferritin |
| url | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1997 |
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