To reveal biomarkers related to macrophage and lactic acid metabolism in renal fibrosis and explore their mechanisms

To reveal biomarkers related to macrophage and lactic acid metabolism in renal fibrosis and explore their mechanisms

IntroductionLactate can influence the fibrotic process by regulating cellular metabolism, inflammatory responses, and cell proliferation, which may be closely related to macrophage function in diseases. Therefore, this research sought to identify biomarkers linked to lactate metabolism and macrophag...

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Main Authors: Chen Yong, Yongfei Yu, Yuan Wei, Guoshun Huang, Lianghui Shu, Kun Gao, Enchao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
lactate metabolism
macrophages
biomarkers
machine learning
renal fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1609903/full
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