Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children
Background. Congenital hydronephrosis is one of the most common abnormalities of the upper urinary tract, which can be exacerbated by a variety of intrinsic or extrinsic triggers. The urinary tract system is one of the major organs complicated by COVID-19 infection. Case Presentations. Here, we repo...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2022/9562671 |
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| author | Masoumeh Mohkam Mahnaz Jamee Farshid Kompani Mitra Khalili Atena Seifi Leily Mohajerzadeh |
| author_facet | Masoumeh Mohkam Mahnaz Jamee Farshid Kompani Mitra Khalili Atena Seifi Leily Mohajerzadeh |
| author_sort | Masoumeh Mohkam |
| collection | DOAJ |
| description | Background. Congenital hydronephrosis is one of the most common abnormalities of the upper urinary tract, which can be exacerbated by a variety of intrinsic or extrinsic triggers. The urinary tract system is one of the major organs complicated by COVID-19 infection. Case Presentations. Here, we report five patients with an established diagnosis of congenital hydronephrosis, who presented with acute abdominal pain and fever and an abrupt increase in the anteroposterior pelvic diameter (APD). Patients had a previous stable course and were under regular follow-up with serial ultrasonographic studies. They underwent surgery or supportive treatment due to the later exacerbation of hydronephrosis. Based on the clinical and imaging findings, no plausible etiologies for these exacerbation episodes, including infection, nephrolithiasis, or abdominal masses, could be postulated. The common aspect in all these patients was the evidence of a COVID-19 infection. Conclusions. Infection with COVID-19 in children with antenatal hydronephrosis may exacerbate the degree of hydronephrosis and renal APD in ultrasonography, which itself may be mediated by the increase in inflammatory mediators. |
| format | Article |
| id | doaj-art-a0144e24941f4b48be0f5e0c1d9baf6d |
| institution | Kabale University |
| issn | 2090-665X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-a0144e24941f4b48be0f5e0c1d9baf6d2025-02-03T01:22:28ZengWileyCase Reports in Nephrology2090-665X2022-01-01202210.1155/2022/9562671Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in ChildrenMasoumeh Mohkam0Mahnaz Jamee1Farshid Kompani2Mitra Khalili3Atena Seifi4Leily Mohajerzadeh5Pediatric Nephrology Research CenterPediatric Nephrology Research CenterDepartment of Pediatric NephrologyDepartment of Pediatric RadiologyPediatric Nephrology Research CenterPediatric Surgery Research CenterBackground. Congenital hydronephrosis is one of the most common abnormalities of the upper urinary tract, which can be exacerbated by a variety of intrinsic or extrinsic triggers. The urinary tract system is one of the major organs complicated by COVID-19 infection. Case Presentations. Here, we report five patients with an established diagnosis of congenital hydronephrosis, who presented with acute abdominal pain and fever and an abrupt increase in the anteroposterior pelvic diameter (APD). Patients had a previous stable course and were under regular follow-up with serial ultrasonographic studies. They underwent surgery or supportive treatment due to the later exacerbation of hydronephrosis. Based on the clinical and imaging findings, no plausible etiologies for these exacerbation episodes, including infection, nephrolithiasis, or abdominal masses, could be postulated. The common aspect in all these patients was the evidence of a COVID-19 infection. Conclusions. Infection with COVID-19 in children with antenatal hydronephrosis may exacerbate the degree of hydronephrosis and renal APD in ultrasonography, which itself may be mediated by the increase in inflammatory mediators.http://dx.doi.org/10.1155/2022/9562671 |
| spellingShingle | Masoumeh Mohkam Mahnaz Jamee Farshid Kompani Mitra Khalili Atena Seifi Leily Mohajerzadeh Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children Case Reports in Nephrology |
| title | Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children |
| title_full | Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children |
| title_fullStr | Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children |
| title_full_unstemmed | Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children |
| title_short | Exacerbation of Congenital Hydronephrosis as the First Presentation of COVID-19 Infection in Children |
| title_sort | exacerbation of congenital hydronephrosis as the first presentation of covid 19 infection in children |
| url | http://dx.doi.org/10.1155/2022/9562671 |
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