Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study
Background/Aim. With the improvement of the outcomes after liver transplantation (LTx), health-related quality of life (HRQoL) and physical activity are becoming significant outcome parameters. We prospectively assessed these parameters in patients with autoimmune and nonautoimmune liver disorders u...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/738297 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561786004439040 |
|---|---|
| author | Katarzyna Kotarska Ewa Wunsch Agnieszka Kempińska-Podhorodecka Joanna Raszeja-Wyszomirska Dimitrios P. Bogdanos Maciej Wójcicki Piotr Milkiewicz |
| author_facet | Katarzyna Kotarska Ewa Wunsch Agnieszka Kempińska-Podhorodecka Joanna Raszeja-Wyszomirska Dimitrios P. Bogdanos Maciej Wójcicki Piotr Milkiewicz |
| author_sort | Katarzyna Kotarska |
| collection | DOAJ |
| description | Background/Aim. With the improvement of the outcomes after liver transplantation (LTx), health-related quality of life (HRQoL) and physical activity are becoming significant outcome parameters. We prospectively assessed these parameters in patients with autoimmune and nonautoimmune liver disorders undergoing LTx. Materials and Methods. Patients (n=107) were subdivided into 3 groups depending on the time after LTx: group-A (n=21): 6–12 months; group-B (n=48): 13–36 months; and group-C (n=38): >37 months. SF-36 and IPAQ were applied in HRQoL and physical activity assessment. Results. Females had impaired HRQoL in most SF-36 domains. Younger patients showed higher scores at SF-36 physical functioning domain but IPAQ was not influenced by age. Group-B had higher general health and physical component summary than group-A (P=0.037, P=0.04, resp.) and total IPAQ than group-C (P=0.047). The sitting time domain was longer in group-A than in group-B and group-C (P=0.0157; P=0.042, resp.). Employed patients had better HRQoL and higher physical activity than those not working. SF-36 and IPAQ were unrelated to the autoimmune etiology of liver disease. Conclusions. These findings show that female and unemployed patients have worse HRQoL, while gender and age at LTx time do not affect IPAQ’s physical activity. The autoimmune etiology of liver disease does not influence HRQoL and physical activity after LTx. |
| format | Article |
| id | doaj-art-a012df6d82d34e9cb7d48ecb1644d2db |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-a012df6d82d34e9cb7d48ecb1644d2db2025-02-03T01:24:18ZengWileyJournal of Immunology Research2314-88612314-71562014-01-01201410.1155/2014/738297738297Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre StudyKatarzyna Kotarska0Ewa Wunsch1Agnieszka Kempińska-Podhorodecka2Joanna Raszeja-Wyszomirska3Dimitrios P. Bogdanos4Maciej Wójcicki5Piotr Milkiewicz6Department of Physical Culture and Health Promotion, University of Szczecin, 70 067 Szczecin, PolandLiver Research Laboratories, Pomeranian Medical University, 70 111 Szczecin, PolandMedical Biology Laboratory, Pomeranian Medical University, 70 111 Szczecin, PolandLiver Research Laboratories, Pomeranian Medical University, 70 111 Szczecin, PolandInstitute of Liver Studies, Division of Liver Transplantation and Mucosal Biology, King’s College London School of Medicine, Denmark Hill Campus, London SE5 9RS, UKLiver and Internal Medicine Unit, Department of General, Transplant and Liver Surgery of the Medical University of Warsaw 02 097 Warsaw, PolandLiver Research Laboratories, Pomeranian Medical University, 70 111 Szczecin, PolandBackground/Aim. With the improvement of the outcomes after liver transplantation (LTx), health-related quality of life (HRQoL) and physical activity are becoming significant outcome parameters. We prospectively assessed these parameters in patients with autoimmune and nonautoimmune liver disorders undergoing LTx. Materials and Methods. Patients (n=107) were subdivided into 3 groups depending on the time after LTx: group-A (n=21): 6–12 months; group-B (n=48): 13–36 months; and group-C (n=38): >37 months. SF-36 and IPAQ were applied in HRQoL and physical activity assessment. Results. Females had impaired HRQoL in most SF-36 domains. Younger patients showed higher scores at SF-36 physical functioning domain but IPAQ was not influenced by age. Group-B had higher general health and physical component summary than group-A (P=0.037, P=0.04, resp.) and total IPAQ than group-C (P=0.047). The sitting time domain was longer in group-A than in group-B and group-C (P=0.0157; P=0.042, resp.). Employed patients had better HRQoL and higher physical activity than those not working. SF-36 and IPAQ were unrelated to the autoimmune etiology of liver disease. Conclusions. These findings show that female and unemployed patients have worse HRQoL, while gender and age at LTx time do not affect IPAQ’s physical activity. The autoimmune etiology of liver disease does not influence HRQoL and physical activity after LTx.http://dx.doi.org/10.1155/2014/738297 |
| spellingShingle | Katarzyna Kotarska Ewa Wunsch Agnieszka Kempińska-Podhorodecka Joanna Raszeja-Wyszomirska Dimitrios P. Bogdanos Maciej Wójcicki Piotr Milkiewicz Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study Journal of Immunology Research |
| title | Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study |
| title_full | Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study |
| title_fullStr | Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study |
| title_full_unstemmed | Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study |
| title_short | Factors Affecting Health-Related Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study |
| title_sort | factors affecting health related quality of life and physical activity after liver transplantation for autoimmune and nonautoimmune liver diseases a prospective single centre study |
| url | http://dx.doi.org/10.1155/2014/738297 |
| work_keys_str_mv | AT katarzynakotarska factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT ewawunsch factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT agnieszkakempinskapodhorodecka factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT joannaraszejawyszomirska factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT dimitriospbogdanos factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT maciejwojcicki factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy AT piotrmilkiewicz factorsaffectinghealthrelatedqualityoflifeandphysicalactivityafterlivertransplantationforautoimmuneandnonautoimmuneliverdiseasesaprospectivesinglecentrestudy |