Cu(OTf)2-catalyzed multicomponent reactions
This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic insights were outlined as well as cycloaddition and aza-Diels...
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Language: | English |
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Beilstein-Institut
2025-01-01
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Series: | Beilstein Journal of Organic Chemistry |
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Online Access: | https://doi.org/10.3762/bjoc.21.7 |
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author | Sara Colombo Camilla Loro Egle M. Beccalli Gianluigi Broggini Marta Papis |
author_facet | Sara Colombo Camilla Loro Egle M. Beccalli Gianluigi Broggini Marta Papis |
author_sort | Sara Colombo |
collection | DOAJ |
description | This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic insights were outlined as well as cycloaddition and aza-Diels–Alder reactions were included. These strategies have gained attention due to their highly atom- and step-economy, one-step multi-bond forming, mild reaction conditions, low cost and easy handling. |
format | Article |
id | doaj-art-a008af45fe9f4d09a2dc77e2f1eebd73 |
institution | Kabale University |
issn | 1860-5397 |
language | English |
publishDate | 2025-01-01 |
publisher | Beilstein-Institut |
record_format | Article |
series | Beilstein Journal of Organic Chemistry |
spelling | doaj-art-a008af45fe9f4d09a2dc77e2f1eebd732025-02-03T09:10:17ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972025-01-0121112214510.3762/bjoc.21.71860-5397-21-7Cu(OTf)2-catalyzed multicomponent reactionsSara Colombo0Camilla Loro1Egle M. Beccalli2Gianluigi Broggini3Marta Papis4Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell’Insubria, Via Valleggio 9, 22100, Como, Italy Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell’Insubria, Via Valleggio 9, 22100, Como, Italy DISFARM, Sezione di Chimica Generale e Organica “A. Marchesini”, Università degli Studi di Milano, Via Venezian 21, 20133, Milano, Italy Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell’Insubria, Via Valleggio 9, 22100, Como, Italy Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell’Insubria, Via Valleggio 9, 22100, Como, Italy This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic insights were outlined as well as cycloaddition and aza-Diels–Alder reactions were included. These strategies have gained attention due to their highly atom- and step-economy, one-step multi-bond forming, mild reaction conditions, low cost and easy handling.https://doi.org/10.3762/bjoc.21.7cascade processcopper catalysisheteropolycyclesmulticomponent reactionsone-pot reaction |
spellingShingle | Sara Colombo Camilla Loro Egle M. Beccalli Gianluigi Broggini Marta Papis Cu(OTf)2-catalyzed multicomponent reactions Beilstein Journal of Organic Chemistry cascade process copper catalysis heteropolycycles multicomponent reactions one-pot reaction |
title | Cu(OTf)2-catalyzed multicomponent reactions |
title_full | Cu(OTf)2-catalyzed multicomponent reactions |
title_fullStr | Cu(OTf)2-catalyzed multicomponent reactions |
title_full_unstemmed | Cu(OTf)2-catalyzed multicomponent reactions |
title_short | Cu(OTf)2-catalyzed multicomponent reactions |
title_sort | cu otf 2 catalyzed multicomponent reactions |
topic | cascade process copper catalysis heteropolycycles multicomponent reactions one-pot reaction |
url | https://doi.org/10.3762/bjoc.21.7 |
work_keys_str_mv | AT saracolombo cuotf2catalyzedmulticomponentreactions AT camillaloro cuotf2catalyzedmulticomponentreactions AT eglembeccalli cuotf2catalyzedmulticomponentreactions AT gianluigibroggini cuotf2catalyzedmulticomponentreactions AT martapapis cuotf2catalyzedmulticomponentreactions |