Modified Carbon Nanotube Paste Electrode for Voltammetric Determination of Carbidopa, Folic Acid, and Tryptophan

A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linea...

Full description

Saved in:
Bibliographic Details
Main Authors: Sakineh Esfandiari Baghbamidi, Hadi Beitollahi, Hassan Karimi-Maleh, Somayeh Soltani-Nejad, Vahhab Soltani-Nejad, Sara Roodsaz
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2012/305872
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A simple and convenient method is described for voltammetric determination of carbidopa (CD), based on its electrochemical oxidation at a modified multiwall carbon nanotube paste electrode. Under optimized conditions, the proposed method exhibited acceptable analytical performances in terms of linearity (over the concentration range from 0.1 to 700.0 μM), detection limit (65.0 nM), and reproducibility (RSD=2.5%) for a solution containing CD. Also, square wave voltammetry (SWV) was used for simultaneous determination of CD, folic acid (FA), and tryptophan (TRP) at the modified electrode. To further validate its possible application, the method was used for the quantification of CD, FA, and TRP in urine samples.
ISSN:2090-8865
2090-8873