Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently been attributed to a voltage differential betwe...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2019/5845839 |
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| _version_ | 1832553561427279872 |
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| author | Gregory Scott Troutman Jason Salamon Matthew Scharf Jeremy A. Mazurek |
| author_facet | Gregory Scott Troutman Jason Salamon Matthew Scharf Jeremy A. Mazurek |
| author_sort | Gregory Scott Troutman |
| collection | DOAJ |
| description | Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently been attributed to a voltage differential between epicardial and endocardial potassium (Ito) currents. While the exact conditions required to induce such waves have been debated, numerous clinical scenarios of environmental and iatrogenic hypothermia have been described. Below, we report a novel case of hypothermia—that of neurosarcoidosis-induced central hypothermia with resultant Osborn waves and other associated findings found on electrocardiogram (ECG). |
| format | Article |
| id | doaj-art-9feaefb56a294b0db721546dae46fb03 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-9feaefb56a294b0db721546dae46fb032025-02-03T05:53:45ZengWileyCase Reports in Cardiology2090-64042090-64122019-01-01201910.1155/2019/58458395845839Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central HypothermiaGregory Scott Troutman0Jason Salamon1Matthew Scharf2Jeremy A. Mazurek3Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USADepartment of Medicine, Division of Cardiology, Morristown Medical Center, Atlantic Medical Group, Morristown, NJ, USADepartment of Medicine, Division of Sleep Medicine, Robert Wood Johnson University Hospital, New Brunswick, NJ, USADepartment of Medicine, Division of Advanced Heart Failure and Transplant Cardiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USAOsborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently been attributed to a voltage differential between epicardial and endocardial potassium (Ito) currents. While the exact conditions required to induce such waves have been debated, numerous clinical scenarios of environmental and iatrogenic hypothermia have been described. Below, we report a novel case of hypothermia—that of neurosarcoidosis-induced central hypothermia with resultant Osborn waves and other associated findings found on electrocardiogram (ECG).http://dx.doi.org/10.1155/2019/5845839 |
| spellingShingle | Gregory Scott Troutman Jason Salamon Matthew Scharf Jeremy A. Mazurek Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia Case Reports in Cardiology |
| title | Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia |
| title_full | Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia |
| title_fullStr | Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia |
| title_full_unstemmed | Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia |
| title_short | Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia |
| title_sort | cold at the core osborn waves in neurosarcoidosis induced central hypothermia |
| url | http://dx.doi.org/10.1155/2019/5845839 |
| work_keys_str_mv | AT gregoryscotttroutman coldatthecoreosbornwavesinneurosarcoidosisinducedcentralhypothermia AT jasonsalamon coldatthecoreosbornwavesinneurosarcoidosisinducedcentralhypothermia AT matthewscharf coldatthecoreosbornwavesinneurosarcoidosisinducedcentralhypothermia AT jeremyamazurek coldatthecoreosbornwavesinneurosarcoidosisinducedcentralhypothermia |