The role of astrocytes in Alzheimer’s disease: a bibliometric analysis
BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder marked by cognitive decline and memory loss. Recent research underscores the crucial role of astrocytes in AD. This study reviews research trends and contributions on astrocytes in AD from 2000 to 2024, shedding light on the evolving...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1481748/full |
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| author | Xiaoqiong An Jun He Jun He Bin Bi Gang Wu Jianwei Xu Jianwei Xu Wenfeng Yu Wenfeng Yu Zhenkui Ren |
| author_facet | Xiaoqiong An Jun He Jun He Bin Bi Gang Wu Jianwei Xu Jianwei Xu Wenfeng Yu Wenfeng Yu Zhenkui Ren |
| author_sort | Xiaoqiong An |
| collection | DOAJ |
| description | BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder marked by cognitive decline and memory loss. Recent research underscores the crucial role of astrocytes in AD. This study reviews research trends and contributions on astrocytes in AD from 2000 to 2024, shedding light on the evolving research landscape.MethodsWe conducted a bibliometric analysis using data from the Web of Science Core Collection, covering publications from January 1, 2000, to July 6, 2024, on “Alzheimer’s disease” and “astrocytes.” We identified 5,252 relevant English articles and reviews. For data visualization and analysis, we used VOSviewer, CiteSpace, and the R package “bibliometrix,” examining collaboration networks, co-citation networks, keyword co-occurrence, and thematic evolution.ResultsBetween 2000 and 2024, 5,252 publications were identified, including 4,125 original research articles and 1,127 review articles. Publications increased significantly after 2016. The United States had the most contributions (1,468), followed by China (836). Major institutions were the University of California system (517) and Harvard University (402). The Journal of Alzheimer’s Disease published the most articles (215). Verkhratsky A was the top author with 51 papers and 1,585 co-citations.ConclusionOur extensive bibliometric analysis indicates a significant increase in research on astrocytes in AD over the past 20 years. This study emphasizes the growing acknowledgment of astrocytes’ crucial role in AD pathogenesis and points to future research on their mechanisms and therapeutic potential. |
| format | Article |
| id | doaj-art-9fcdf1c678af4e1d9d9c93f6bb07c1f1 |
| institution | OA Journals |
| issn | 1663-4365 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj-art-9fcdf1c678af4e1d9d9c93f6bb07c1f12025-08-20T02:05:21ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652024-11-011610.3389/fnagi.2024.14817481481748The role of astrocytes in Alzheimer’s disease: a bibliometric analysisXiaoqiong An0Jun He1Jun He2Bin Bi3Gang Wu4Jianwei Xu5Jianwei Xu6Wenfeng Yu7Wenfeng Yu8Zhenkui Ren9Department of Laboratory Medicine, The Second People's Hospital of Guizhou Province, Guiyang, ChinaDepartment of Laboratory Medicine, The Second People's Hospital of Guizhou Province, Guiyang, ChinaKey Laboratory of Molecular Biology, Guizhou Medical University, Guiyang, Guizhou, ChinaKey Laboratory of Human Brain Bank for Functions and Diseases of Department of Education of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou, ChinaKey Laboratory of Human Brain Bank for Functions and Diseases of Department of Education of Guizhou Province, Guizhou Medical University, Guiyang, Guizhou, ChinaGuizhou Provincial Center for Clinical Laboratory, Guiyang, ChinaCenter for Tissue Engineering and Stem Cell Research, Guizhou Medical University, Guiyang, ChinaPsychosomatic Department, The Second People's Hospital of Guizhou Province, Guiyang, ChinaDepartment of Pharmacology, School of Basic Medicine, Guizhou Medical University, Guiyang, ChinaDepartment of Laboratory Medicine, The Second People's Hospital of Guizhou Province, Guiyang, ChinaBackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder marked by cognitive decline and memory loss. Recent research underscores the crucial role of astrocytes in AD. This study reviews research trends and contributions on astrocytes in AD from 2000 to 2024, shedding light on the evolving research landscape.MethodsWe conducted a bibliometric analysis using data from the Web of Science Core Collection, covering publications from January 1, 2000, to July 6, 2024, on “Alzheimer’s disease” and “astrocytes.” We identified 5,252 relevant English articles and reviews. For data visualization and analysis, we used VOSviewer, CiteSpace, and the R package “bibliometrix,” examining collaboration networks, co-citation networks, keyword co-occurrence, and thematic evolution.ResultsBetween 2000 and 2024, 5,252 publications were identified, including 4,125 original research articles and 1,127 review articles. Publications increased significantly after 2016. The United States had the most contributions (1,468), followed by China (836). Major institutions were the University of California system (517) and Harvard University (402). The Journal of Alzheimer’s Disease published the most articles (215). Verkhratsky A was the top author with 51 papers and 1,585 co-citations.ConclusionOur extensive bibliometric analysis indicates a significant increase in research on astrocytes in AD over the past 20 years. This study emphasizes the growing acknowledgment of astrocytes’ crucial role in AD pathogenesis and points to future research on their mechanisms and therapeutic potential.https://www.frontiersin.org/articles/10.3389/fnagi.2024.1481748/fullAlzheimer’s diseaseastrocytesbibliometrixCiteSpaceVOSviewer |
| spellingShingle | Xiaoqiong An Jun He Jun He Bin Bi Gang Wu Jianwei Xu Jianwei Xu Wenfeng Yu Wenfeng Yu Zhenkui Ren The role of astrocytes in Alzheimer’s disease: a bibliometric analysis Frontiers in Aging Neuroscience Alzheimer’s disease astrocytes bibliometrix CiteSpace VOSviewer |
| title | The role of astrocytes in Alzheimer’s disease: a bibliometric analysis |
| title_full | The role of astrocytes in Alzheimer’s disease: a bibliometric analysis |
| title_fullStr | The role of astrocytes in Alzheimer’s disease: a bibliometric analysis |
| title_full_unstemmed | The role of astrocytes in Alzheimer’s disease: a bibliometric analysis |
| title_short | The role of astrocytes in Alzheimer’s disease: a bibliometric analysis |
| title_sort | role of astrocytes in alzheimer s disease a bibliometric analysis |
| topic | Alzheimer’s disease astrocytes bibliometrix CiteSpace VOSviewer |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1481748/full |
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