Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
In this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chrom...
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Wiley
2020-01-01
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Series: | Journal of Analytical Methods in Chemistry |
Online Access: | http://dx.doi.org/10.1155/2020/8875788 |
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author | Xianwen Yue Fangfei Xu Peng Lv Huailei Yang Huiwei Bao Yang Xu |
author_facet | Xianwen Yue Fangfei Xu Peng Lv Huailei Yang Huiwei Bao Yang Xu |
author_sort | Xianwen Yue |
collection | DOAJ |
description | In this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chromones as indexes. Furthermore, the optimum extraction conditions were confirmed using a single-factor test and response surface optimization test. Scavenging activities of DPPH anion and ABTS cation radicals of different SR extracts (DES, methanol, and ethanol) were studied. The analysis results of best extraction conditions optimized by Design-Expert software were as follows: extraction time (40 min), extraction temperature (60°C), and the solid/liquid ratio (32 mL/g). Scavenging rates of the DES extract for DPPH anion radical and ABTS cation radical were found to be 75.31% and 65.71%, which were higher than those of methanol and ethanol extracts. In conclusion, the developed extraction method can be regarded as a safe, green, and more effective approach for the extraction of chromones in SR. |
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id | doaj-art-9fbd5ece5e5d4442baeeb1d02e93082a |
institution | Kabale University |
issn | 2090-8865 2090-8873 |
language | English |
publishDate | 2020-01-01 |
publisher | Wiley |
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series | Journal of Analytical Methods in Chemistry |
spelling | doaj-art-9fbd5ece5e5d4442baeeb1d02e93082a2025-02-03T06:43:42ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732020-01-01202010.1155/2020/88757888875788Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents ExtractionXianwen Yue0Fangfei Xu1Peng Lv2Huailei Yang3Huiwei Bao4Yang Xu5College of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaPlant Chemistry Laboratory, Chinese Institute of Jilin Ginseng, Changchun 130033, ChinaCollege of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaPharmaceutical Department, The Second Hospital of Jilin University, Changchun 130000, ChinaCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, ChinaCollege of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaIn this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chromones as indexes. Furthermore, the optimum extraction conditions were confirmed using a single-factor test and response surface optimization test. Scavenging activities of DPPH anion and ABTS cation radicals of different SR extracts (DES, methanol, and ethanol) were studied. The analysis results of best extraction conditions optimized by Design-Expert software were as follows: extraction time (40 min), extraction temperature (60°C), and the solid/liquid ratio (32 mL/g). Scavenging rates of the DES extract for DPPH anion radical and ABTS cation radical were found to be 75.31% and 65.71%, which were higher than those of methanol and ethanol extracts. In conclusion, the developed extraction method can be regarded as a safe, green, and more effective approach for the extraction of chromones in SR.http://dx.doi.org/10.1155/2020/8875788 |
spellingShingle | Xianwen Yue Fangfei Xu Peng Lv Huailei Yang Huiwei Bao Yang Xu Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction Journal of Analytical Methods in Chemistry |
title | Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction |
title_full | Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction |
title_fullStr | Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction |
title_full_unstemmed | Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction |
title_short | Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction |
title_sort | analysis of antioxidant capacity of chromones in saposhnikoviae radix obtained by ultrasonic assisted deep eutectic solvents extraction |
url | http://dx.doi.org/10.1155/2020/8875788 |
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