Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction

In this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chrom...

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Main Authors: Xianwen Yue, Fangfei Xu, Peng Lv, Huailei Yang, Huiwei Bao, Yang Xu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2020/8875788
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author Xianwen Yue
Fangfei Xu
Peng Lv
Huailei Yang
Huiwei Bao
Yang Xu
author_facet Xianwen Yue
Fangfei Xu
Peng Lv
Huailei Yang
Huiwei Bao
Yang Xu
author_sort Xianwen Yue
collection DOAJ
description In this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chromones as indexes. Furthermore, the optimum extraction conditions were confirmed using a single-factor test and response surface optimization test. Scavenging activities of DPPH anion and ABTS cation radicals of different SR extracts (DES, methanol, and ethanol) were studied. The analysis results of best extraction conditions optimized by Design-Expert software were as follows: extraction time (40 min), extraction temperature (60°C), and the solid/liquid ratio (32 mL/g). Scavenging rates of the DES extract for DPPH anion radical and ABTS cation radical were found to be 75.31% and 65.71%, which were higher than those of methanol and ethanol extracts. In conclusion, the developed extraction method can be regarded as a safe, green, and more effective approach for the extraction of chromones in SR.
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institution Kabale University
issn 2090-8865
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language English
publishDate 2020-01-01
publisher Wiley
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series Journal of Analytical Methods in Chemistry
spelling doaj-art-9fbd5ece5e5d4442baeeb1d02e93082a2025-02-03T06:43:42ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732020-01-01202010.1155/2020/88757888875788Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents ExtractionXianwen Yue0Fangfei Xu1Peng Lv2Huailei Yang3Huiwei Bao4Yang Xu5College of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaPlant Chemistry Laboratory, Chinese Institute of Jilin Ginseng, Changchun 130033, ChinaCollege of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaPharmaceutical Department, The Second Hospital of Jilin University, Changchun 130000, ChinaCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, ChinaCollege of Pharmacy, Baicheng Medical College, Baicheng 137000, ChinaIn this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR). The extraction effects of 11 prepared DESs were screened taking contents of chromones as indexes. Furthermore, the optimum extraction conditions were confirmed using a single-factor test and response surface optimization test. Scavenging activities of DPPH anion and ABTS cation radicals of different SR extracts (DES, methanol, and ethanol) were studied. The analysis results of best extraction conditions optimized by Design-Expert software were as follows: extraction time (40 min), extraction temperature (60°C), and the solid/liquid ratio (32 mL/g). Scavenging rates of the DES extract for DPPH anion radical and ABTS cation radical were found to be 75.31% and 65.71%, which were higher than those of methanol and ethanol extracts. In conclusion, the developed extraction method can be regarded as a safe, green, and more effective approach for the extraction of chromones in SR.http://dx.doi.org/10.1155/2020/8875788
spellingShingle Xianwen Yue
Fangfei Xu
Peng Lv
Huailei Yang
Huiwei Bao
Yang Xu
Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
Journal of Analytical Methods in Chemistry
title Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
title_full Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
title_fullStr Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
title_full_unstemmed Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
title_short Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction
title_sort analysis of antioxidant capacity of chromones in saposhnikoviae radix obtained by ultrasonic assisted deep eutectic solvents extraction
url http://dx.doi.org/10.1155/2020/8875788
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