ADRB2 is regulated by TRIM22 and facilitates lung adenocarcinoma progression via JAK2/STAT3 signaling pathway

ADRB2 is regulated by TRIM22 and facilitates lung adenocarcinoma progression via JAK2/STAT3 signaling pathway

Abstract Lung adenocarcinoma (LUAD) is the most common pathological subtype of lung cancer. Adrenergic signal has always been considered as an important link with the occurrence and development of cancer. Considerable evidence suggests that β-2 adrenergic receptor (ADRB2) shows an important role in...

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Bibliographic Details
Main Authors: Mingming Xu, Song Han, Mingjun Yang, Jianle Chen, Yifei Liu, Youlang Zhou, Jiahai Shi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
β-2 adrenergic receptor (ADRB2)
Lung adenocarcinoma (LUAD)
TRIM22
JAK2/STAT3 signaling pathway
Cell cycle
Online Access:https://doi.org/10.1038/s41598-025-06017-6
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