Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria
The iCARE Nigeria study is evaluating a daily text message medication reminder intervention (TXTXT) to improve viral suppression and medication adherence among youth living with HIV (YLH), aged 15–24 years. In this sub-study, we evaluated text message responsiveness (text-back) at 24 weeks of the in...
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MDPI AG
2025-05-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/10/5/137 |
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| author | Mobolanle Balogun Aniekan E. Ulor Mayowa Odofin Olufunmilola Idowu Mmeli V. Chukwu Abiola Aina Oluwanifemi Adeshina Hameed Adelabu Lisa M. Kuhns Amy K. Johnson Kehinde M. Kuti Nadia A. Sam-Agudu Titilope Badru Marbella Cervantes Robert Garofalo Babafemi Taiwo Alani S. Akanmu |
| author_facet | Mobolanle Balogun Aniekan E. Ulor Mayowa Odofin Olufunmilola Idowu Mmeli V. Chukwu Abiola Aina Oluwanifemi Adeshina Hameed Adelabu Lisa M. Kuhns Amy K. Johnson Kehinde M. Kuti Nadia A. Sam-Agudu Titilope Badru Marbella Cervantes Robert Garofalo Babafemi Taiwo Alani S. Akanmu |
| author_sort | Mobolanle Balogun |
| collection | DOAJ |
| description | The iCARE Nigeria study is evaluating a daily text message medication reminder intervention (TXTXT) to improve viral suppression and medication adherence among youth living with HIV (YLH), aged 15–24 years. In this sub-study, we evaluated text message responsiveness (text-back) at 24 weeks of the intervention as an indicator of engagement, as well as barriers and facilitators at one of six clinical study sites. Differences in responses by age group, birth sex, schooling status, education, mode of infection, and weekend/weekday and holiday/non-holiday periods were analyzed using <i>t</i>-test and multiple linear regression. Focus group discussions were conducted among three groups (low, average, and high text message responsiveness) and analyzed using a rapid content analysis approach. Overall, TXTXT responsiveness was 26.5% (4606/17,367); older age (18–24 years) and weekdays (versus weekends) were significantly associated with higher responsiveness. Facilitators included being comfortable receiving personalized text messages. Barriers included a lack of airtime and messages received late. Overall, text-back responsiveness to daily medication adherence messages among YLH was low, better among older participants, and higher on weekdays. Addressing barriers and promoting facilitators may improve responsiveness. |
| format | Article |
| id | doaj-art-9f8210c901c64d29b3b9ea8f8974ee70 |
| institution | OA Journals |
| issn | 2414-6366 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj-art-9f8210c901c64d29b3b9ea8f8974ee702025-08-20T02:33:48ZengMDPI AGTropical Medicine and Infectious Disease2414-63662025-05-0110513710.3390/tropicalmed10050137Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest NigeriaMobolanle Balogun0Aniekan E. Ulor1Mayowa Odofin2Olufunmilola Idowu3Mmeli V. Chukwu4Abiola Aina5Oluwanifemi Adeshina6Hameed Adelabu7Lisa M. Kuhns8Amy K. Johnson9Kehinde M. Kuti10Nadia A. Sam-Agudu11Titilope Badru12Marbella Cervantes13Robert Garofalo14Babafemi Taiwo15Alani S. Akanmu16Department of Community Health and Primary Care, College of Medicine, University of Lagos, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USADepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USAInfectious Disease Institute, College of Medicine, University of Ibadan and Staff Medical Services Department, University College Hospital, Ibadan 200285, NigeriaInternational Research Centre of Excellence, Institute of Human Virology Nigeria, Abuja 900231, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaDivision of Adolescent and Young Adult Medicine, Ann and Robert H Lurie Children’s Hospital of Chicago, Chicago, IL 60208, USADepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USADivision of Infectious Diseases and Institute for Global Health, Northwestern University, Chicago, IL 60611, USADepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos 12003, NigeriaThe iCARE Nigeria study is evaluating a daily text message medication reminder intervention (TXTXT) to improve viral suppression and medication adherence among youth living with HIV (YLH), aged 15–24 years. In this sub-study, we evaluated text message responsiveness (text-back) at 24 weeks of the intervention as an indicator of engagement, as well as barriers and facilitators at one of six clinical study sites. Differences in responses by age group, birth sex, schooling status, education, mode of infection, and weekend/weekday and holiday/non-holiday periods were analyzed using <i>t</i>-test and multiple linear regression. Focus group discussions were conducted among three groups (low, average, and high text message responsiveness) and analyzed using a rapid content analysis approach. Overall, TXTXT responsiveness was 26.5% (4606/17,367); older age (18–24 years) and weekdays (versus weekends) were significantly associated with higher responsiveness. Facilitators included being comfortable receiving personalized text messages. Barriers included a lack of airtime and messages received late. Overall, text-back responsiveness to daily medication adherence messages among YLH was low, better among older participants, and higher on weekdays. Addressing barriers and promoting facilitators may improve responsiveness.https://www.mdpi.com/2414-6366/10/5/137adolescentmedication adherenceHIVtext messagingNigeria |
| spellingShingle | Mobolanle Balogun Aniekan E. Ulor Mayowa Odofin Olufunmilola Idowu Mmeli V. Chukwu Abiola Aina Oluwanifemi Adeshina Hameed Adelabu Lisa M. Kuhns Amy K. Johnson Kehinde M. Kuti Nadia A. Sam-Agudu Titilope Badru Marbella Cervantes Robert Garofalo Babafemi Taiwo Alani S. Akanmu Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria Tropical Medicine and Infectious Disease adolescent medication adherence HIV text messaging Nigeria |
| title | Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria |
| title_full | Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria |
| title_fullStr | Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria |
| title_full_unstemmed | Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria |
| title_short | Patterns, Barriers and Facilitators of Responsiveness to Text Message Medication Reminders Among Youth Living with HIV in Southwest Nigeria |
| title_sort | patterns barriers and facilitators of responsiveness to text message medication reminders among youth living with hiv in southwest nigeria |
| topic | adolescent medication adherence HIV text messaging Nigeria |
| url | https://www.mdpi.com/2414-6366/10/5/137 |
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