Review of electrophysiological models to study membrane potential changes in breast cancer cell transformation and tumor progression

Review of electrophysiological models to study membrane potential changes in breast cancer cell transformation and tumor progression

The transformation of normal breast cells into cancerous cells is a complex process influenced by both genetic and microenvironmental factors. Recent studies highlight the significant role of membrane potential (Vm) alterations in this transformation. Cancer cells typically exhibit a depolarized res...

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Bibliographic Details
Main Authors: Chitaranjan Mahapatra, Arnaw Kishore, Jineetkumar Gawad, Ahmed Al-Emam, Riad Azzam Kouzeiha, Maher Ali Rusho
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
Subjects:
breast cancer
membrane potential
ion channels
gap junction
calcium dynamics
electrophysiological model
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1536165/full
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