Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review

ABSTRACT Diabetes is one of the most pressing health issues in the Southeast Asian region, and hypertension has been commonly reported as a comorbidity in adults with diabetes. This systematic review aimed to synthesize evidence on the prevalence and management of hypertension in adults with diabete...

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Main Authors: Wei Jin Wong, Tan Van Nguyen, Fahed Ahmad, Huyen Thi Thanh Vu, Angela S. Koh, Kit Mun Tan, Ying Zhang, Christopher Harrison, Mark Woodward, Tu Ngoc Nguyen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14936
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author Wei Jin Wong
Tan Van Nguyen
Fahed Ahmad
Huyen Thi Thanh Vu
Angela S. Koh
Kit Mun Tan
Ying Zhang
Christopher Harrison
Mark Woodward
Tu Ngoc Nguyen
author_facet Wei Jin Wong
Tan Van Nguyen
Fahed Ahmad
Huyen Thi Thanh Vu
Angela S. Koh
Kit Mun Tan
Ying Zhang
Christopher Harrison
Mark Woodward
Tu Ngoc Nguyen
author_sort Wei Jin Wong
collection DOAJ
description ABSTRACT Diabetes is one of the most pressing health issues in the Southeast Asian region, and hypertension has been commonly reported as a comorbidity in adults with diabetes. This systematic review aimed to synthesize evidence on the prevalence and management of hypertension in adults with diabetes in Southeast Asian countries. A literature search was conducted in Ovid MEDLINE and Embase Classic + Embase from database inception until March 15, 2024. Studies were included if (1) they were conducted in Southeast Asian countries, (2) the study populations were adults with diabetes, and (3) there was information related to hypertension or blood pressure (BP) in the study results. Of the 7486 abstracts found, 90 studies qualified for this review. Most studies reported a hypertension prevalence of 70% or higher (ranging from 29.4% to 93.4%). Despite this high prevalence, a substantial proportion of these populations did not receive adequate BP control, with most studies indicating a control rate of less than 40%. There was limited evidence on the prescription of antihypertensive therapies and medication adherence. There was a lack of studies from 4 of the 11 countries in the region. This review highlights that BP control in adults with diabetes remains a significant challenge in Southeast Asia. Given the ongoing epidemiological transition, and the increasing older population in this region who are likely to accumulate multiple chronic conditions complicating medication strategies, this review highlights the urgent need to improve BP management in those with diabetes.
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spelling doaj-art-9f73696d38db43198ca021a151aad5202025-01-31T05:38:37ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762025-01-01271n/an/a10.1111/jch.14936Hypertension in Adults With Diabetes in Southeast Asia: A Systematic ReviewWei Jin Wong0Tan Van Nguyen1Fahed Ahmad2Huyen Thi Thanh Vu3Angela S. Koh4Kit Mun Tan5Ying Zhang6Christopher Harrison7Mark Woodward8Tu Ngoc Nguyen9Faculty of Medicine and Health University of Sydney Sydney NSW AustraliaDepartment of Geriatrics and Gerontology University of Medicine and Pharmacy Ho Chi Minh City VietnamFaculty of Medicine and Health University of Sydney Sydney NSW AustraliaDepartment of Geriatrics Hanoi Medical University Hanoi VietnamNational Heart Centre Singapore SingaporeFaculty of Medicine Universiti Malaya Kuala Lumpur MalaysiaFaculty of Medicine and Health University of Sydney Sydney NSW AustraliaFaculty of Medicine and Health University of Sydney Sydney NSW AustraliaThe George Institute for Global Health University of New South Wales Sydney NSW AustraliaFaculty of Medicine and Health University of Sydney Sydney NSW AustraliaABSTRACT Diabetes is one of the most pressing health issues in the Southeast Asian region, and hypertension has been commonly reported as a comorbidity in adults with diabetes. This systematic review aimed to synthesize evidence on the prevalence and management of hypertension in adults with diabetes in Southeast Asian countries. A literature search was conducted in Ovid MEDLINE and Embase Classic + Embase from database inception until March 15, 2024. Studies were included if (1) they were conducted in Southeast Asian countries, (2) the study populations were adults with diabetes, and (3) there was information related to hypertension or blood pressure (BP) in the study results. Of the 7486 abstracts found, 90 studies qualified for this review. Most studies reported a hypertension prevalence of 70% or higher (ranging from 29.4% to 93.4%). Despite this high prevalence, a substantial proportion of these populations did not receive adequate BP control, with most studies indicating a control rate of less than 40%. There was limited evidence on the prescription of antihypertensive therapies and medication adherence. There was a lack of studies from 4 of the 11 countries in the region. This review highlights that BP control in adults with diabetes remains a significant challenge in Southeast Asia. Given the ongoing epidemiological transition, and the increasing older population in this region who are likely to accumulate multiple chronic conditions complicating medication strategies, this review highlights the urgent need to improve BP management in those with diabetes.https://doi.org/10.1111/jch.14936agingblood pressure controldiabeteshypertensionmedication adherenceSoutheast Asia
spellingShingle Wei Jin Wong
Tan Van Nguyen
Fahed Ahmad
Huyen Thi Thanh Vu
Angela S. Koh
Kit Mun Tan
Ying Zhang
Christopher Harrison
Mark Woodward
Tu Ngoc Nguyen
Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
The Journal of Clinical Hypertension
aging
blood pressure control
diabetes
hypertension
medication adherence
Southeast Asia
title Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
title_full Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
title_fullStr Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
title_full_unstemmed Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
title_short Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review
title_sort hypertension in adults with diabetes in southeast asia a systematic review
topic aging
blood pressure control
diabetes
hypertension
medication adherence
Southeast Asia
url https://doi.org/10.1111/jch.14936
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AT angelaskoh hypertensioninadultswithdiabetesinsoutheastasiaasystematicreview
AT kitmuntan hypertensioninadultswithdiabetesinsoutheastasiaasystematicreview
AT yingzhang hypertensioninadultswithdiabetesinsoutheastasiaasystematicreview
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