Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient
Introduction: Hyperactivity immune responses to coronavirus disease 2019 (COVID-19) can lead to several manifestations in the human organ. One of the most affected organs is the respiratory system. Not only does it affect the respiratory system, but hyperactivity can also affect the neuromuscular a...
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The Journal of Infection in Developing Countries
2023-11-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/17975 |
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| author | Yulia Devina Suci Alfian Nur Rosyid Nurwapina Langga Wulaa Muh Alamsyah Irmayani AK Tamsil Bachrun |
| author_facet | Yulia Devina Suci Alfian Nur Rosyid Nurwapina Langga Wulaa Muh Alamsyah Irmayani AK Tamsil Bachrun |
| author_sort | Yulia Devina Suci |
| collection | DOAJ |
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Introduction: Hyperactivity immune responses to coronavirus disease 2019 (COVID-19) can lead to several manifestations in the human organ. One of the most affected organs is the respiratory system. Not only does it affect the respiratory system, but hyperactivity can also affect the neuromuscular and cerebrovascular systems, though it is scarce for both systems to be affected simultaneously.
Case presentation: We presented a mild COVID-19 patient with a history of progressive general weakness and dysphagia on day seventh day after patient was first diagnosed with COVID-19, which continued with diplopia and shortness of breath. The patient experienced respiratory failure type 1 and was admitted to an intensive care unit. A head CT scan showed multiple lacunar infarcts in the nucleus lentiform, while the electromyography (EMG) showed Guillain-Barré syndrome (GBS) with the subtype acute inflammatory demyelinating polyneuropathy (AIDP). The patient was reported to have successful therapy with intravenous immunoglobulin (IVIG) for five days and physical rehabilitation for three months. General weakness disappeared after the therapy, and the patient could do regular daily activities.
Conclusions: Various neurological symptoms can manifest in COVID-19 patients. Acute progressive muscle weakness should be considered as an autoimmune and cerebrovascular disease induced by COVID-19. Early diagnosis and treatment can provide a better outcome for the patient.
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| format | Article |
| id | doaj-art-9f72c0f7240a4f68a704fef798dec1cc |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-9f72c0f7240a4f68a704fef798dec1cc2025-08-20T02:27:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-11-01171110.3855/jidc.17975Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patientYulia Devina Suci0Alfian Nur Rosyid1Nurwapina Langga Wulaa2Muh Alamsyah3Irmayani AK4Tamsil Bachrun5Department of Pulmonology and Respiratory Medicine, Dr. Soetomo Academic Hospital, Universitas Airlangga Faculty of Medicine, IndonesiaDepartment of Pulmonology and Respiratory Medicine, Dr. Soetomo Academic Hospital, Universitas Airlangga Faculty of Medicine, IndonesiaDepartment of Neurology, Dr. Wahidin Sudirohusodo Hospital, Universitas Hasanuddin Faculty of Medicine, South Sulawesi, IndonesiaDepartment of Emergency, Kendari City Hospital, South East Sulawesi, IndonesiaDepartment of Neurology Bahteramas Hospital, South East Sulawesi, IndonesiaDepartmen of Anesthesiology and Intensive Care, Bahteramas Hospital, South East Sulawesi, Indonesia Introduction: Hyperactivity immune responses to coronavirus disease 2019 (COVID-19) can lead to several manifestations in the human organ. One of the most affected organs is the respiratory system. Not only does it affect the respiratory system, but hyperactivity can also affect the neuromuscular and cerebrovascular systems, though it is scarce for both systems to be affected simultaneously. Case presentation: We presented a mild COVID-19 patient with a history of progressive general weakness and dysphagia on day seventh day after patient was first diagnosed with COVID-19, which continued with diplopia and shortness of breath. The patient experienced respiratory failure type 1 and was admitted to an intensive care unit. A head CT scan showed multiple lacunar infarcts in the nucleus lentiform, while the electromyography (EMG) showed Guillain-Barré syndrome (GBS) with the subtype acute inflammatory demyelinating polyneuropathy (AIDP). The patient was reported to have successful therapy with intravenous immunoglobulin (IVIG) for five days and physical rehabilitation for three months. General weakness disappeared after the therapy, and the patient could do regular daily activities. Conclusions: Various neurological symptoms can manifest in COVID-19 patients. Acute progressive muscle weakness should be considered as an autoimmune and cerebrovascular disease induced by COVID-19. Early diagnosis and treatment can provide a better outcome for the patient. https://jidc.org/index.php/journal/article/view/17975Guillain-Barré syndromemultiple lacunar infarct strokesSARS-CoV-2infectious disease |
| spellingShingle | Yulia Devina Suci Alfian Nur Rosyid Nurwapina Langga Wulaa Muh Alamsyah Irmayani AK Tamsil Bachrun Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient Journal of Infection in Developing Countries Guillain-Barré syndrome multiple lacunar infarct strokes SARS-CoV-2 infectious disease |
| title | Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient |
| title_full | Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient |
| title_fullStr | Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient |
| title_full_unstemmed | Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient |
| title_short | Guillain-Barré Syndrome and multiple lacunar infarcts in a COVID-19 patient |
| title_sort | guillain barre syndrome and multiple lacunar infarcts in a covid 19 patient |
| topic | Guillain-Barré syndrome multiple lacunar infarct strokes SARS-CoV-2 infectious disease |
| url | https://jidc.org/index.php/journal/article/view/17975 |
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