Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture.

Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture.

Induced pluripotent stem cell derived hepatocytes (IPSC-Heps) have the potential to reduce the demand for a dwindling number of primary cells used in applications ranging from therapeutic cell infusions to in vitro toxicology studies. However, current differentiation protocols and culture methods pr...

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Bibliographic Details
Main Authors: Richard L Gieseck, Nicholas R F Hannan, Roque Bort, Neil A Hanley, Rosemary A L Drake, Grant W W Cameron, Thomas A Wynn, Ludovic Vallier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0086372
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