Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers

Acral ischemia/necrosis is one of the rarest but most dreadful complications of thrombotic microangiopathy in pediatric patients. It is more reported with thrombotic thrombocytopenic purpura than with hemolytic and uremic syndrome. Even with anticoagulant therapy, it is often irreversible, leading t...

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Main Authors: H. Nassih, Z. Lazrak, S. Younous
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2020/8869883
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author H. Nassih
Z. Lazrak
S. Younous
author_facet H. Nassih
Z. Lazrak
S. Younous
author_sort H. Nassih
collection DOAJ
description Acral ischemia/necrosis is one of the rarest but most dreadful complications of thrombotic microangiopathy in pediatric patients. It is more reported with thrombotic thrombocytopenic purpura than with hemolytic and uremic syndrome. Even with anticoagulant therapy, it is often irreversible, leading to amputation.
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institution Kabale University
issn 2090-6803
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publishDate 2020-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-9f61a8d850604617b26bbe484bfeb1752025-02-03T06:05:39ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/88698838869883Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two ToddlersH. Nassih0Z. Lazrak1S. Younous2From B Pediatric Ward, Department of Pediatrics, Child and Mother Hospital, Mohammed VI University Hospital Center, Marrakesh Medical and Pharmacy Faculty, Caddy Ayad University, Marrakesh, MoroccoFrom B Pediatric Ward, Department of Pediatrics, Child and Mother Hospital, Mohammed VI University Hospital Center, Marrakesh Medical and Pharmacy Faculty, Caddy Ayad University, Marrakesh, MoroccoFrom the Pediatric Intensive Care Unit, Department of Pediatrics, Child and Mother Hospital, Mohammed VI University Hospital Center, Marrakesh Medical and Pharmacy Faculty, Caddy Ayad University, Marrakesh, MoroccoAcral ischemia/necrosis is one of the rarest but most dreadful complications of thrombotic microangiopathy in pediatric patients. It is more reported with thrombotic thrombocytopenic purpura than with hemolytic and uremic syndrome. Even with anticoagulant therapy, it is often irreversible, leading to amputation.http://dx.doi.org/10.1155/2020/8869883
spellingShingle H. Nassih
Z. Lazrak
S. Younous
Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
Case Reports in Pediatrics
title Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
title_full Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
title_fullStr Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
title_full_unstemmed Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
title_short Severe Acral Necrosis Complicating Thrombotic Microangiopathy in Two Toddlers
title_sort severe acral necrosis complicating thrombotic microangiopathy in two toddlers
url http://dx.doi.org/10.1155/2020/8869883
work_keys_str_mv AT hnassih severeacralnecrosiscomplicatingthromboticmicroangiopathyintwotoddlers
AT zlazrak severeacralnecrosiscomplicatingthromboticmicroangiopathyintwotoddlers
AT syounous severeacralnecrosiscomplicatingthromboticmicroangiopathyintwotoddlers