Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers
IntroductionAlthough the effects of ionizing radiation on radiation workers have been extensively studied in China, no prospective cohort study has been conducted in Chongqing. Furthermore, previous cohorts have not provided a broad-gauge assessment of the temporal relationship between low-dose occu...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1531546/full |
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| author | Xiao-Ling Qin Qiang Huang Han-Wen Zhang Yi Zeng Xian-Shu Lin Xiao-Yuan Fan Jun Diao Cheng-Zhi Chen Shu-Qun Cheng Fang Yuan Jun-Lin He Wei Li Yin-Yin Xia |
| author_facet | Xiao-Ling Qin Qiang Huang Han-Wen Zhang Yi Zeng Xian-Shu Lin Xiao-Yuan Fan Jun Diao Cheng-Zhi Chen Shu-Qun Cheng Fang Yuan Jun-Lin He Wei Li Yin-Yin Xia |
| author_sort | Xiao-Ling Qin |
| collection | DOAJ |
| description | IntroductionAlthough the effects of ionizing radiation on radiation workers have been extensively studied in China, no prospective cohort study has been conducted in Chongqing. Furthermore, previous cohorts have not provided a broad-gauge assessment of the temporal relationship between low-dose occupational radiation exposure and the risk of health outcomes.MethodsA prospective cohort study will be carried out focusing on radiation workers in Chongqing. Health examination outcomes and radiation dose monitoring data will be collected and analyzed using the distributed lag non-linear model (DLNM) combined with generalized additive model (GAM) or generalized linear model (GLM) to evaluate the exposure-lag response relationship.DiscussionOur study will enhance our understanding of the exposure-lag response association between occupational radiation exposure and the health of radiation workers based on DLNM.Clinical trial registrationChinese Clinical Trials Registry, ChiCTR2400081804. |
| format | Article |
| id | doaj-art-9f4c8a9a092d4764a86fbdbba5a6bb9c |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-9f4c8a9a092d4764a86fbdbba5a6bb9c2025-01-27T06:40:54ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011310.3389/fpubh.2025.15315461531546Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation WorkersXiao-Ling Qin0Qiang Huang1Han-Wen Zhang2Yi Zeng3Xian-Shu Lin4Xiao-Yuan Fan5Jun Diao6Cheng-Zhi Chen7Shu-Qun Cheng8Fang Yuan9Jun-Lin He10Wei Li11Yin-Yin Xia12School of Public Health, Chongqing Medical University, Chongqing, ChinaChongqing Center for Disease Control and Prevention, Chongqing, ChinaDepartment of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaChongqing Jiulongpo District Center for Disease Control and Prevention, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaChongqing Center for Disease Control and Prevention, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaChongqing Center for Disease Control and Prevention, Chongqing, ChinaSchool of Public Health, Chongqing Medical University, Chongqing, ChinaIntroductionAlthough the effects of ionizing radiation on radiation workers have been extensively studied in China, no prospective cohort study has been conducted in Chongqing. Furthermore, previous cohorts have not provided a broad-gauge assessment of the temporal relationship between low-dose occupational radiation exposure and the risk of health outcomes.MethodsA prospective cohort study will be carried out focusing on radiation workers in Chongqing. Health examination outcomes and radiation dose monitoring data will be collected and analyzed using the distributed lag non-linear model (DLNM) combined with generalized additive model (GAM) or generalized linear model (GLM) to evaluate the exposure-lag response relationship.DiscussionOur study will enhance our understanding of the exposure-lag response association between occupational radiation exposure and the health of radiation workers based on DLNM.Clinical trial registrationChinese Clinical Trials Registry, ChiCTR2400081804.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1531546/fullradiation workerslow-dose ionizing radiationexposure–lag responsecohortdistributed lag non-linear model |
| spellingShingle | Xiao-Ling Qin Qiang Huang Han-Wen Zhang Yi Zeng Xian-Shu Lin Xiao-Yuan Fan Jun Diao Cheng-Zhi Chen Shu-Qun Cheng Fang Yuan Jun-Lin He Wei Li Yin-Yin Xia Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers Frontiers in Public Health radiation workers low-dose ionizing radiation exposure–lag response cohort distributed lag non-linear model |
| title | Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers |
| title_full | Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers |
| title_fullStr | Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers |
| title_full_unstemmed | Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers |
| title_short | Low-dose ionizing radiation and the exposure–lag response: protocol for a prospective cohort study on The Health Effects of Chongqing Occupational Radiation Workers |
| title_sort | low dose ionizing radiation and the exposure lag response protocol for a prospective cohort study on the health effects of chongqing occupational radiation workers |
| topic | radiation workers low-dose ionizing radiation exposure–lag response cohort distributed lag non-linear model |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1531546/full |
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