Influenza and Bacterial Pathogen Coinfections in the 20th Century
To help understand the potential impact of bacterial coinfection during pandemic influenza periods, we undertook a far-reaching review of the existing literature to gain insights into the interaction of influenza and bacterial pathogens. Reports published between 1950 and 2006 were identified from s...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2011/146376 |
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| _version_ | 1832558263828217856 |
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| author | Xuan-Yi Wang Paul E. Kilgore Kyung Ah Lim Song-Mei Wang Jeongseok Lee Wei Deng Mei-Qi Mo Batmunkh Nyambat Jing-Chen Ma Michael O. Favorov John D. Clemens |
| author_facet | Xuan-Yi Wang Paul E. Kilgore Kyung Ah Lim Song-Mei Wang Jeongseok Lee Wei Deng Mei-Qi Mo Batmunkh Nyambat Jing-Chen Ma Michael O. Favorov John D. Clemens |
| author_sort | Xuan-Yi Wang |
| collection | DOAJ |
| description | To help understand the potential impact of bacterial coinfection during pandemic influenza periods, we undertook a far-reaching review of the existing literature to gain insights into the interaction of influenza and bacterial pathogens. Reports published between 1950 and 2006 were identified from scientific citation databases using standardized search terms. Study outcomes related to coinfection were subjected to a pooled analysis. Coinfection with influenza and bacterial pathogens occurred more frequently in pandemic compared with seasonal influenza periods. The most common bacterial coinfections with influenza virus were due to S. pneumoniae, H. influenzae, Staphylococcus spp., and Streptococcus spp. Of these, S. pneumoniae was the most common cause of bacterial coinfection with influenza and accounted for 40.8% and 16.6% of bacterial coinfections during pandemic and seasonal periods, respectively. These results suggest that bacterial pathogens will play a key role in many countries, as the H1N1(A) influenza pandemic moves forward. Given the role of bacterial coinfections during influenza epidemics and pandemics, the conduct of well-designed field evaluations of public health measures to reduce the burden of these common bacterial pathogens and influenza in at-risk populations is warranted. |
| format | Article |
| id | doaj-art-9f46923905a047848d41b6cbcd1cd3ad |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-9f46923905a047848d41b6cbcd1cd3ad2025-02-03T01:32:54ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982011-01-01201110.1155/2011/146376146376Influenza and Bacterial Pathogen Coinfections in the 20th CenturyXuan-Yi Wang0Paul E. Kilgore1Kyung Ah Lim2Song-Mei Wang3Jeongseok Lee4Wei Deng5Mei-Qi Mo6Batmunkh Nyambat7Jing-Chen Ma8Michael O. Favorov9John D. Clemens10Center for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, ChinaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaLaboratory of Medical Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, ChinaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaDepartment of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, ChinaCenter for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, ChinaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaCenter for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, ChinaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaInternational Vaccine Institute, Seoul 151-818, Republic of KoreaTo help understand the potential impact of bacterial coinfection during pandemic influenza periods, we undertook a far-reaching review of the existing literature to gain insights into the interaction of influenza and bacterial pathogens. Reports published between 1950 and 2006 were identified from scientific citation databases using standardized search terms. Study outcomes related to coinfection were subjected to a pooled analysis. Coinfection with influenza and bacterial pathogens occurred more frequently in pandemic compared with seasonal influenza periods. The most common bacterial coinfections with influenza virus were due to S. pneumoniae, H. influenzae, Staphylococcus spp., and Streptococcus spp. Of these, S. pneumoniae was the most common cause of bacterial coinfection with influenza and accounted for 40.8% and 16.6% of bacterial coinfections during pandemic and seasonal periods, respectively. These results suggest that bacterial pathogens will play a key role in many countries, as the H1N1(A) influenza pandemic moves forward. Given the role of bacterial coinfections during influenza epidemics and pandemics, the conduct of well-designed field evaluations of public health measures to reduce the burden of these common bacterial pathogens and influenza in at-risk populations is warranted.http://dx.doi.org/10.1155/2011/146376 |
| spellingShingle | Xuan-Yi Wang Paul E. Kilgore Kyung Ah Lim Song-Mei Wang Jeongseok Lee Wei Deng Mei-Qi Mo Batmunkh Nyambat Jing-Chen Ma Michael O. Favorov John D. Clemens Influenza and Bacterial Pathogen Coinfections in the 20th Century Interdisciplinary Perspectives on Infectious Diseases |
| title | Influenza and Bacterial Pathogen Coinfections in the 20th Century |
| title_full | Influenza and Bacterial Pathogen Coinfections in the 20th Century |
| title_fullStr | Influenza and Bacterial Pathogen Coinfections in the 20th Century |
| title_full_unstemmed | Influenza and Bacterial Pathogen Coinfections in the 20th Century |
| title_short | Influenza and Bacterial Pathogen Coinfections in the 20th Century |
| title_sort | influenza and bacterial pathogen coinfections in the 20th century |
| url | http://dx.doi.org/10.1155/2011/146376 |
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