Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance

Recently, it has been suggested that metabolic syndrome should be considered a premorbid condition in younger individuals. We evaluated the prevalence of metabolic syndrome in Estonia and compared the characteristic profiles between morbid metabolic syndrome (previously established diabetes, hyperte...

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Main Authors: Triin Eglit, Tarvo Rajasalu, Margus Lember
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/951672
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author Triin Eglit
Tarvo Rajasalu
Margus Lember
author_facet Triin Eglit
Tarvo Rajasalu
Margus Lember
author_sort Triin Eglit
collection DOAJ
description Recently, it has been suggested that metabolic syndrome should be considered a premorbid condition in younger individuals. We evaluated the prevalence of metabolic syndrome in Estonia and compared the characteristic profiles between morbid metabolic syndrome (previously established diabetes, hypertension, or dyslipidaemia) and premorbid metabolic syndrome subgroups. Our study was a cross-sectional, population-based sample of the general population in Estonia aged 20–74 years (n=495). Metabolic syndrome was diagnosed by National Cholesterol Education Program Adult Treatment Panel III criteria. Insulin resistance was estimated using the homeostasis model assessment (HOMA-IR). The crude and weighted prevalence of metabolic syndrome was 27.9% and 25.9%, respectively. Despite being significantly younger, the premorbid subgroup showed similar levels of insulin resistance as the morbid subgroup (mean HOMA-IR ± SD 2.73±1.8 versus 2.97±2.1, P=0.5). The most important attribute of metabolic syndrome is insulin resistance, which already characterises metabolic syndrome in the early stages of its metabolic abnormalities.
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spelling doaj-art-9f446ef621fc49f3941618abb84b3d982025-02-03T01:33:12ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/951672951672Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin ResistanceTriin Eglit0Tarvo Rajasalu1Margus Lember2Department of Internal Medicine, University of Tartu, 6 L. Puusepa Street, 51014 Tartu, EstoniaDepartment of Internal Medicine, University of Tartu, 6 L. Puusepa Street, 51014 Tartu, EstoniaDepartment of Internal Medicine, University of Tartu, 6 L. Puusepa Street, 51014 Tartu, EstoniaRecently, it has been suggested that metabolic syndrome should be considered a premorbid condition in younger individuals. We evaluated the prevalence of metabolic syndrome in Estonia and compared the characteristic profiles between morbid metabolic syndrome (previously established diabetes, hypertension, or dyslipidaemia) and premorbid metabolic syndrome subgroups. Our study was a cross-sectional, population-based sample of the general population in Estonia aged 20–74 years (n=495). Metabolic syndrome was diagnosed by National Cholesterol Education Program Adult Treatment Panel III criteria. Insulin resistance was estimated using the homeostasis model assessment (HOMA-IR). The crude and weighted prevalence of metabolic syndrome was 27.9% and 25.9%, respectively. Despite being significantly younger, the premorbid subgroup showed similar levels of insulin resistance as the morbid subgroup (mean HOMA-IR ± SD 2.73±1.8 versus 2.97±2.1, P=0.5). The most important attribute of metabolic syndrome is insulin resistance, which already characterises metabolic syndrome in the early stages of its metabolic abnormalities.http://dx.doi.org/10.1155/2012/951672
spellingShingle Triin Eglit
Tarvo Rajasalu
Margus Lember
Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
International Journal of Endocrinology
title Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
title_full Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
title_fullStr Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
title_full_unstemmed Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
title_short Metabolic Syndrome in Estonia: Prevalence and Associations with Insulin Resistance
title_sort metabolic syndrome in estonia prevalence and associations with insulin resistance
url http://dx.doi.org/10.1155/2012/951672
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AT tarvorajasalu metabolicsyndromeinestoniaprevalenceandassociationswithinsulinresistance
AT marguslember metabolicsyndromeinestoniaprevalenceandassociationswithinsulinresistance