Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question

In low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate...

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Main Authors: Brandon A. Kohrt, Dristy Gurung, Ritika Singh, Sauharda Rai, Mani Neupane, Elizabeth L. Turner, Alyssa Platt, Shifeng Sun, Kamal Gautam, Nagendra P. Luitel, Mark J.D. Jordans
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Epidemiology and Psychiatric Sciences
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Online Access:https://www.cambridge.org/core/product/identifier/S2045796025000010/type/journal_article
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author Brandon A. Kohrt
Dristy Gurung
Ritika Singh
Sauharda Rai
Mani Neupane
Elizabeth L. Turner
Alyssa Platt
Shifeng Sun
Kamal Gautam
Nagendra P. Luitel
Mark J.D. Jordans
author_facet Brandon A. Kohrt
Dristy Gurung
Ritika Singh
Sauharda Rai
Mani Neupane
Elizabeth L. Turner
Alyssa Platt
Shifeng Sun
Kamal Gautam
Nagendra P. Luitel
Mark J.D. Jordans
author_sort Brandon A. Kohrt
collection DOAJ
description In low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate diagnoses is a major bottleneck to reducing the global mental health treatment gap. In this commentary, we argue that current research practices are insufficient to generate the evidence needed to improve diagnostic accuracy. Research studies commonly determine accurate diagnosis by relying on self-report tools such as the Patient Health Questionnaire-9. This is problematic because self-report tools often overestimate prevalence, primarily due to their high rates of false positives. Moreover, nearly all studies on detection focus solely on depression, not taking into account the spectrum of conditions on which primary healthcare workers are being trained. Single condition self-report tools fail to discriminate among different types of mental health conditions, leading to a heterogeneous group of conditions masked under a single scale. As an alternative path forward, we propose improving research on diagnostic accuracy to better evaluate the reach of mental health service delivery in primary care. We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as ‘good-enough’ diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. Clinically meaningful identification can be operationalized differently across settings based on what level of diagnostic specificity is needed to select from available treatments. Rethinking research strategies to evaluate accuracy of diagnosis is vital to improve training, supervision and delivery of mental health services around the world.
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spelling doaj-art-9f35aacc7bcf4acb9957ba75fe29d2bf2025-01-30T04:03:33ZengCambridge University PressEpidemiology and Psychiatric Sciences2045-79602045-79792025-01-013410.1017/S2045796025000010Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that questionBrandon A. Kohrt0https://orcid.org/0000-0002-3829-4820Dristy Gurung1https://orcid.org/0000-0003-1839-9382Ritika Singh2https://orcid.org/0000-0001-5039-4835Sauharda Rai3https://orcid.org/0000-0002-9393-1466Mani Neupane4https://orcid.org/0000-0002-7383-1089Elizabeth L. Turner5https://orcid.org/0000-0002-7638-5942Alyssa Platt6Shifeng Sun7Kamal Gautam8https://orcid.org/0000-0001-9401-9359Nagendra P. Luitel9https://orcid.org/0000-0002-8291-0205Mark J.D. Jordans10https://orcid.org/0000-0001-5925-8039Center for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA Research Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, NepalResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, NepalCenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USACenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USAResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, NepalDepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, Durham NC, USADepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, Durham NC, USADepartment of Biostatistics and Bioinformatics and Duke Global Health Institute, Duke University, Durham NC, USACenter for Global Mental Health Equity, Department of Psychiatry and Behavioral Health, George Washington University, Washington, DC, USA Research Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, NepalResearch Department, Transcultural Psychosocial Organization Nepal (TPO Nepal), Kathmandu, NepalHealth Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, Center for Global Mental Health, King’s College London, London, UKIn low- and middle-income countries, fewer than 1 in 10 people with mental health conditions are estimated to be accurately diagnosed in primary care. This is despite more than 90 countries providing mental health training for primary healthcare workers in the past two decades. The lack of accurate diagnoses is a major bottleneck to reducing the global mental health treatment gap. In this commentary, we argue that current research practices are insufficient to generate the evidence needed to improve diagnostic accuracy. Research studies commonly determine accurate diagnosis by relying on self-report tools such as the Patient Health Questionnaire-9. This is problematic because self-report tools often overestimate prevalence, primarily due to their high rates of false positives. Moreover, nearly all studies on detection focus solely on depression, not taking into account the spectrum of conditions on which primary healthcare workers are being trained. Single condition self-report tools fail to discriminate among different types of mental health conditions, leading to a heterogeneous group of conditions masked under a single scale. As an alternative path forward, we propose improving research on diagnostic accuracy to better evaluate the reach of mental health service delivery in primary care. We recommend evaluating multiple conditions, statistically adjusting prevalence estimates generated from self-report tools, and consistently using structured clinical interviews as a gold standard. We propose clinically meaningful detection as ‘good-enough’ diagnoses incorporating multiple conditions accounting for context, health system and types of interventions available. Clinically meaningful identification can be operationalized differently across settings based on what level of diagnostic specificity is needed to select from available treatments. Rethinking research strategies to evaluate accuracy of diagnosis is vital to improve training, supervision and delivery of mental health services around the world.https://www.cambridge.org/core/product/identifier/S2045796025000010/type/journal_articledepressiondeveloping countriesdiagnosisglobal healthprimary carepsychiatric status rating scalespsychosisscreening
spellingShingle Brandon A. Kohrt
Dristy Gurung
Ritika Singh
Sauharda Rai
Mani Neupane
Elizabeth L. Turner
Alyssa Platt
Shifeng Sun
Kamal Gautam
Nagendra P. Luitel
Mark J.D. Jordans
Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
Epidemiology and Psychiatric Sciences
depression
developing countries
diagnosis
global health
primary care
psychiatric status rating scales
psychosis
screening
title Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
title_full Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
title_fullStr Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
title_full_unstemmed Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
title_short Is there a mental health diagnostic crisis in primary care? Current research practices in global mental health cannot answer that question
title_sort is there a mental health diagnostic crisis in primary care current research practices in global mental health cannot answer that question
topic depression
developing countries
diagnosis
global health
primary care
psychiatric status rating scales
psychosis
screening
url https://www.cambridge.org/core/product/identifier/S2045796025000010/type/journal_article
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