Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies

Objective To provide a route map regarding systematic reviews (SRs) of acupuncture therapies that will meet two goals: (1) to identify areas in which more or better evidence is required and (2) to identify acupuncture applications that, although proven effective, remain underused in practice, and th...

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Main Authors: Yuqing Zhang, Gordon Guyatt, Lin Wang, Hao Wen, Liming Lu, Gabriel Rada, Lai Wang, Shuqi Ge, Yu Dong, Camila Ávila, Xiaorong Tang, Neng-Gui Xu, Zhao Zeng, Camilo Vergara, Rouhao Chen, Xiaojing Wei, Wen Luo, Jing chun Zeng, Chun-Zhi Tang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/6/e056803.full
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author Yuqing Zhang
Gordon Guyatt
Lin Wang
Hao Wen
Liming Lu
Gabriel Rada
Lai Wang
Shuqi Ge
Yu Dong
Camila Ávila
Xiaorong Tang
Neng-Gui Xu
Zhao Zeng
Camilo Vergara
Rouhao Chen
Xiaojing Wei
Wen Luo
Jing chun Zeng
Chun-Zhi Tang
author_facet Yuqing Zhang
Gordon Guyatt
Lin Wang
Hao Wen
Liming Lu
Gabriel Rada
Lai Wang
Shuqi Ge
Yu Dong
Camila Ávila
Xiaorong Tang
Neng-Gui Xu
Zhao Zeng
Camilo Vergara
Rouhao Chen
Xiaojing Wei
Wen Luo
Jing chun Zeng
Chun-Zhi Tang
author_sort Yuqing Zhang
collection DOAJ
description Objective To provide a route map regarding systematic reviews (SRs) of acupuncture therapies that will meet two goals: (1) to identify areas in which more or better evidence is required and (2) to identify acupuncture applications that, although proven effective, remain underused in practice, and thus warrant more effective knowledge dissemination.Eligibility criteria We included SRs that conducted meta-analyses (MAs) of randomised controlled trials (RCTs) for this overview.Information sources We searched for SRs without language restrictions from January 2015 to November 2020 in four Chinese electronic databases and Epistemonikos database. And we also searched for newly published RCTs that were eligible for selected best SRs in PubMed, Medline, Cochrane Central Register of Controlled Trials, Embase and four Chinese electronic databases from its lasted search dates to November 2020.Synthesis of results We reanalysed the selected MAs if new primary studies were added. We used random-effect model to calculate the overall effect.Results Our search identified 120 SRs published in the last 5 years addressing acupuncture therapies across 12 therapeutic areas and 77 diseases and conditions. The SRs included 205 outcomes and involved 138 995 participants from 1402 RCTs. We constructed 77 evidence matrices, including 120 SRs and their included RCTs in the Epistemonikos database. Seventy-seven SRs represented the effect estimate of acupuncture therapies. Finally, we system summarised the areas of possible underutilisation of acupuncture therapies (high or moderate certainty evidence of large or moderate effects), and the areas of warranting additional investigation of acupuncture therapies (low or very low certainty evidence of moderate or large effects).Conclusion The evidence maps and overview of SRs on acupuncture therapies identified both therapies with substantial benefits that may require more assertive evidence dissemination and promising acupuncture therapies that require further investigation.
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spelling doaj-art-9f274985df3346cdafb7fbf7527d7b132025-01-28T00:15:09ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-056803Evidence mapping and overview of systematic reviews of the effects of acupuncture therapiesYuqing Zhang0Gordon Guyatt1Lin Wang2Hao Wen3Liming Lu4Gabriel Rada5Lai Wang6Shuqi Ge7Yu Dong8Camila Ávila9Xiaorong Tang10Neng-Gui Xu11Zhao Zeng12Camilo Vergara13Rouhao Chen14Xiaojing Wei15Wen Luo16Jing chun Zeng17Chun-Zhi Tang183 The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA1 Department of Medicine, McMaster University, Hamilton, Ontario, Canada3 Jiangsu Provincial People`s Hospital, Nanjing, Chinaresearcher,South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, China10 Evidence-Based Healthcare Program, Pontificia Universidad Católica de Chile, Santiago, Chile1BeiGene, Beijing, Chinaresearcher,researcher,consultant,South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, ChinaSouth China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China4 Library of Guangzhou University of Chinese Medicine, Guangzhou, ChinaEpistemonikos Foundation, Santiago, Chileresearcher,researcher,Department of Pediatrics, New York Medical College, Valhalla, New York, USADepartment of Acupuncture, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaSouth China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, ChinaObjective To provide a route map regarding systematic reviews (SRs) of acupuncture therapies that will meet two goals: (1) to identify areas in which more or better evidence is required and (2) to identify acupuncture applications that, although proven effective, remain underused in practice, and thus warrant more effective knowledge dissemination.Eligibility criteria We included SRs that conducted meta-analyses (MAs) of randomised controlled trials (RCTs) for this overview.Information sources We searched for SRs without language restrictions from January 2015 to November 2020 in four Chinese electronic databases and Epistemonikos database. And we also searched for newly published RCTs that were eligible for selected best SRs in PubMed, Medline, Cochrane Central Register of Controlled Trials, Embase and four Chinese electronic databases from its lasted search dates to November 2020.Synthesis of results We reanalysed the selected MAs if new primary studies were added. We used random-effect model to calculate the overall effect.Results Our search identified 120 SRs published in the last 5 years addressing acupuncture therapies across 12 therapeutic areas and 77 diseases and conditions. The SRs included 205 outcomes and involved 138 995 participants from 1402 RCTs. We constructed 77 evidence matrices, including 120 SRs and their included RCTs in the Epistemonikos database. Seventy-seven SRs represented the effect estimate of acupuncture therapies. Finally, we system summarised the areas of possible underutilisation of acupuncture therapies (high or moderate certainty evidence of large or moderate effects), and the areas of warranting additional investigation of acupuncture therapies (low or very low certainty evidence of moderate or large effects).Conclusion The evidence maps and overview of SRs on acupuncture therapies identified both therapies with substantial benefits that may require more assertive evidence dissemination and promising acupuncture therapies that require further investigation.https://bmjopen.bmj.com/content/12/6/e056803.full
spellingShingle Yuqing Zhang
Gordon Guyatt
Lin Wang
Hao Wen
Liming Lu
Gabriel Rada
Lai Wang
Shuqi Ge
Yu Dong
Camila Ávila
Xiaorong Tang
Neng-Gui Xu
Zhao Zeng
Camilo Vergara
Rouhao Chen
Xiaojing Wei
Wen Luo
Jing chun Zeng
Chun-Zhi Tang
Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
BMJ Open
title Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
title_full Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
title_fullStr Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
title_full_unstemmed Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
title_short Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
title_sort evidence mapping and overview of systematic reviews of the effects of acupuncture therapies
url https://bmjopen.bmj.com/content/12/6/e056803.full
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