Research progress of immune checkpoint inhibitors in neoadjuvant immunotherapy for dMMR/MSI-H locally advanced colorectal cancer

Research progress of immune checkpoint inhibitors in neoadjuvant immunotherapy for dMMR/MSI-H locally advanced colorectal cancer

In recent years, immune checkpoint inhibitors (ICIs) have made great progress in the treatment of colorectal cancer, particularly in the post-line and first-line treatment of dMMR/MSH-H metastatic colorectal cancer patients, demonstrating good clinical outcomes. Currently, the relevant research and...

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Bibliographic Details
Main Authors: Zhu Xi, Li Yang, Jiang Jun, Li Guoli, Kao Xiaoming
Format: Article
Language:zho
Published: Editorial Office of Journal of Colorectal & Anal Surgery 2024-02-01
Series:结直肠肛门外科
Subjects:
locally advanced colorectal cancer
immunotherapy
immune checkpoint inhibitors
neoadjuvant therapy
Online Access:https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=67&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC1%E6%9C%9F
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Summary:In recent years, immune checkpoint inhibitors (ICIs) have made great progress in the treatment of colorectal cancer, particularly in the post-line and first-line treatment of dMMR/MSH-H metastatic colorectal cancer patients, demonstrating good clinical outcomes. Currently, the relevant research and exploration on the use of ICIs in neoadjuvant immunotherapy are still ongoing. This article mainly introduces the research progress of ICIs in neoadjuvant immunotherapy for dMMR/MSI-H locally advanced colorectal cancer, aiming to provide new method references for neoadjuvant immunotherapy of locally advanced colorectal cancer.
ISSN:1674-0491

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