Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials
Abstract Mussel periostracum, a nonliving multifunctional gel that covers the rigid inorganic shells of mussels, provides protection against mechanical impacts, biofouling, and corrosion in harsh ocean environments. The inner part of the periostracum, which emerges from biological tissues, functions...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-04-01
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| Series: | NPG Asia Materials |
| Online Access: | https://doi.org/10.1038/s41427-024-00543-x |
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| author | Hyungbin Kim Heejin Lim Sangsik Kim Jun Mo Koo Chanoong Lim Hojung Kwak Dongyeop X. Oh Dong Soo Hwang |
| author_facet | Hyungbin Kim Heejin Lim Sangsik Kim Jun Mo Koo Chanoong Lim Hojung Kwak Dongyeop X. Oh Dong Soo Hwang |
| author_sort | Hyungbin Kim |
| collection | DOAJ |
| description | Abstract Mussel periostracum, a nonliving multifunctional gel that covers the rigid inorganic shells of mussels, provides protection against mechanical impacts, biofouling, and corrosion in harsh ocean environments. The inner part of the periostracum, which emerges from biological tissues, functions as a natural interface between tissue and inorganic materials. The periostracum shows significant potential for application in implantable devices that provide interfaces; however, this system remains unexplored. In this study, we revealed that the inner periostracum performs graded mechanical functions and efficiently dissipates energy to accommodate differences in stiffness and stress types on both sides. On the tissue end, the lightly pigmented periostracum exhibits extensibility and energy dissipation under repetitive tension. This process was facilitated by the slipping and reassembly of β-strands in the discovered major proteins, which we named periostracin proteins. On the shell end, the highly pigmented, mineralized, and porous segment of the periostracum provided stiffness and cushioned against compressive stresses exerted by the shell valves during closure. These findings offer a novel possibilities for the design of interfaces that bridge human tissue and devices. |
| format | Article |
| id | doaj-art-9f186080848a44008fff2b361087ffdd |
| institution | Kabale University |
| issn | 1884-4057 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | NPG Asia Materials |
| spelling | doaj-art-9f186080848a44008fff2b361087ffdd2025-01-19T12:28:24ZengNature PortfolioNPG Asia Materials1884-40572024-04-0116111310.1038/s41427-024-00543-xInvestigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materialsHyungbin Kim0Heejin Lim1Sangsik Kim2Jun Mo Koo3Chanoong Lim4Hojung Kwak5Dongyeop X. Oh6Dong Soo Hwang7Division of Environmental Science and Engineering, Pohang University of Science and Technology (POSTECH)Center for Scientific Instrumentation, Korea Basic Science Institute (KBSI)Department of Energy Chemical Engineering, Kyungpook National UniversityDepartment of Organic Materials Engineering, Chungnam National UniversitySchool of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology (UNIST)Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT)Department of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Inha UniversityDivision of Environmental Science and Engineering, Pohang University of Science and Technology (POSTECH)Abstract Mussel periostracum, a nonliving multifunctional gel that covers the rigid inorganic shells of mussels, provides protection against mechanical impacts, biofouling, and corrosion in harsh ocean environments. The inner part of the periostracum, which emerges from biological tissues, functions as a natural interface between tissue and inorganic materials. The periostracum shows significant potential for application in implantable devices that provide interfaces; however, this system remains unexplored. In this study, we revealed that the inner periostracum performs graded mechanical functions and efficiently dissipates energy to accommodate differences in stiffness and stress types on both sides. On the tissue end, the lightly pigmented periostracum exhibits extensibility and energy dissipation under repetitive tension. This process was facilitated by the slipping and reassembly of β-strands in the discovered major proteins, which we named periostracin proteins. On the shell end, the highly pigmented, mineralized, and porous segment of the periostracum provided stiffness and cushioned against compressive stresses exerted by the shell valves during closure. These findings offer a novel possibilities for the design of interfaces that bridge human tissue and devices.https://doi.org/10.1038/s41427-024-00543-x |
| spellingShingle | Hyungbin Kim Heejin Lim Sangsik Kim Jun Mo Koo Chanoong Lim Hojung Kwak Dongyeop X. Oh Dong Soo Hwang Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials NPG Asia Materials |
| title | Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials |
| title_full | Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials |
| title_fullStr | Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials |
| title_full_unstemmed | Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials |
| title_short | Investigation on mussel periostracum, a viscoelastic-to-poro-gel graded material, as an interface between soft tissue and rigid materials |
| title_sort | investigation on mussel periostracum a viscoelastic to poro gel graded material as an interface between soft tissue and rigid materials |
| url | https://doi.org/10.1038/s41427-024-00543-x |
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