Signal sequences target enzymes and structural proteins to bacterial microcompartments and are critical for microcompartment formation

ABSTRACT Spatial organization of pathway enzymes has emerged as a promising tool to address several challenges in metabolic engineering, such as flux imbalances and off-target product formation. Bacterial microcompartments (MCPs) are a spatial organization strategy used natively by many bacteria to...

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Bibliographic Details
Main Authors: Elizabeth R. Johnson, Nolan W. Kennedy, Carolyn E. Mills, Shiqi Liang, Swetha Chandrasekar, Taylor M. Nichols, Grant A. Rybnicky, Danielle Tullman-Ercek
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00962-24
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