HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis

HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis

Introduction: Abnormal alternative splicing (AS) contributes to aggressive intrahepatic invasion and metastatic spread, leading to the high lethality of hepatocellular carcinoma (HCC). Objectives: This study aims to investigate the functional implications of UPF3B-S (a truncated oncogenic splice var...

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Bibliographic Details
Main Authors: Hong Wang, Dong Qian, Jiabei Wang, Yao Liu, Wenguang Luo, Hongyan Zhang, Jingjing Cheng, Heng Li, Yang Wu, Wuhan Li, Jing Wang, Xia Yang, Tianzhi Zhang, Dong Han, Qinyao Wang, Chris Zhiyi Zhang, Lianxin Liu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Advanced Research
Subjects:
Alternative splicing
Hepatocellular carcinoma
Invasion and metastasis
UPF3B-S
HnRNPR
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224000729
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