Colorectal Carcinoma with Extremely Low CA19-9
Aim. The aim of this study is to determine the significance of postoperative sequential measurements of serum CA19-9 in patients with extremely low serum level. Patients and Methods. Serum level of CA19-9 of 1096 patients who underwent surgery was measured preoperatively and every three months after...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2009/780263 |
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| author | Yutaka J. Kawamura Aika Tokumitsu Junichi Sasaki Shingo Tsujinaka Takafumi Maeda Ken Mizogami Fumio Konishi |
| author_facet | Yutaka J. Kawamura Aika Tokumitsu Junichi Sasaki Shingo Tsujinaka Takafumi Maeda Ken Mizogami Fumio Konishi |
| author_sort | Yutaka J. Kawamura |
| collection | DOAJ |
| description | Aim. The aim of this study is to determine the significance of postoperative sequential measurements of serum CA19-9 in patients with extremely low serum level. Patients and Methods. Serum level of CA19-9 of 1096 patients who underwent surgery was measured preoperatively and every three months after surgery for 5 years. Patients with CA19-9 level of less than 2 U/mL at the time of diagnosis were defined as Extremely Low CA19-9 (ELCA). Results. One hundred and seven patients (9.8%) were ELCA. Of these, 86 underwent surgery with curative intent. Serum levels of CA19-9 in patients who did not undergo curative resection (𝑁=12) and who developed recurrence (𝑁=10) were less than 2.0 U/mL in all occasions during followup. In all patients without recurrence, serum level of CA19-9 also remained less than 2.0 U/mL. Conclusion. In patients with extremely low CA19-9, who consist of 9.8% of colorectal carcinoma cases, postoperative sequential measurement of serum level of CA19-9 contributed neither to assessment of curability of surgical resection nor to detection of recurrence. |
| format | Article |
| id | doaj-art-9f045b0bbd9e497a8e1caf4778989035 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-9f045b0bbd9e497a8e1caf47789890352025-02-03T06:45:19ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/780263780263Colorectal Carcinoma with Extremely Low CA19-9Yutaka J. Kawamura0Aika Tokumitsu1Junichi Sasaki2Shingo Tsujinaka3Takafumi Maeda4Ken Mizogami5Fumio Konishi6Department of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanAim. The aim of this study is to determine the significance of postoperative sequential measurements of serum CA19-9 in patients with extremely low serum level. Patients and Methods. Serum level of CA19-9 of 1096 patients who underwent surgery was measured preoperatively and every three months after surgery for 5 years. Patients with CA19-9 level of less than 2 U/mL at the time of diagnosis were defined as Extremely Low CA19-9 (ELCA). Results. One hundred and seven patients (9.8%) were ELCA. Of these, 86 underwent surgery with curative intent. Serum levels of CA19-9 in patients who did not undergo curative resection (𝑁=12) and who developed recurrence (𝑁=10) were less than 2.0 U/mL in all occasions during followup. In all patients without recurrence, serum level of CA19-9 also remained less than 2.0 U/mL. Conclusion. In patients with extremely low CA19-9, who consist of 9.8% of colorectal carcinoma cases, postoperative sequential measurement of serum level of CA19-9 contributed neither to assessment of curability of surgical resection nor to detection of recurrence.http://dx.doi.org/10.1155/2009/780263 |
| spellingShingle | Yutaka J. Kawamura Aika Tokumitsu Junichi Sasaki Shingo Tsujinaka Takafumi Maeda Ken Mizogami Fumio Konishi Colorectal Carcinoma with Extremely Low CA19-9 Gastroenterology Research and Practice |
| title | Colorectal Carcinoma with Extremely Low CA19-9 |
| title_full | Colorectal Carcinoma with Extremely Low CA19-9 |
| title_fullStr | Colorectal Carcinoma with Extremely Low CA19-9 |
| title_full_unstemmed | Colorectal Carcinoma with Extremely Low CA19-9 |
| title_short | Colorectal Carcinoma with Extremely Low CA19-9 |
| title_sort | colorectal carcinoma with extremely low ca19 9 |
| url | http://dx.doi.org/10.1155/2009/780263 |
| work_keys_str_mv | AT yutakajkawamura colorectalcarcinomawithextremelylowca199 AT aikatokumitsu colorectalcarcinomawithextremelylowca199 AT junichisasaki colorectalcarcinomawithextremelylowca199 AT shingotsujinaka colorectalcarcinomawithextremelylowca199 AT takafumimaeda colorectalcarcinomawithextremelylowca199 AT kenmizogami colorectalcarcinomawithextremelylowca199 AT fumiokonishi colorectalcarcinomawithextremelylowca199 |