Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke

Guillain–Barré syndrome (GBS) is a heterogeneous disease, and it usually develops after an antecedent infection, while rare cases develop following a central nervous system disease. Given the indeterminacy of prodromal infection symptoms and the overlap of symptoms with other neurological disorders,...

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Main Authors: Da Xu, Cheng Yu, Xue-Jun Deng, Man Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403561/full
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author Da Xu
Cheng Yu
Xue-Jun Deng
Man Li
author_facet Da Xu
Cheng Yu
Xue-Jun Deng
Man Li
author_sort Da Xu
collection DOAJ
description Guillain–Barré syndrome (GBS) is a heterogeneous disease, and it usually develops after an antecedent infection, while rare cases develop following a central nervous system disease. Given the indeterminacy of prodromal infection symptoms and the overlap of symptoms with other neurological disorders, a rigorous clinical and neurological examination in conjunction with history is necessary for early diagnosis and treatment of GBS. Here we present a rare case of GBS following acute ischemic stroke which was different from previous reports such as GBS following hemorrhagic stroke or head trauma. Moreover, intravenous immunoglobulin was effective in this patient after 6 months of follow-up despite the potential risk of thrombotic events.
format Article
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issn 1664-3224
language English
publishDate 2024-11-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Immunology
spelling doaj-art-9efdb54ac52d4a17a3ba685cd95f6b4c2025-08-20T02:27:42ZengFrontiers Media S.A.Frontiers in Immunology1664-32242024-11-011510.3389/fimmu.2024.14035611403561Case report: Guillain-Barré syndrome following acute ischemic brainstem strokeDa XuCheng YuXue-Jun DengMan LiGuillain–Barré syndrome (GBS) is a heterogeneous disease, and it usually develops after an antecedent infection, while rare cases develop following a central nervous system disease. Given the indeterminacy of prodromal infection symptoms and the overlap of symptoms with other neurological disorders, a rigorous clinical and neurological examination in conjunction with history is necessary for early diagnosis and treatment of GBS. Here we present a rare case of GBS following acute ischemic stroke which was different from previous reports such as GBS following hemorrhagic stroke or head trauma. Moreover, intravenous immunoglobulin was effective in this patient after 6 months of follow-up despite the potential risk of thrombotic events.https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403561/fullGuillain-Barré syndromeacute ischemic strokeintravenous immunoglobulindiagnosiscase report
spellingShingle Da Xu
Cheng Yu
Xue-Jun Deng
Man Li
Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
Frontiers in Immunology
Guillain-Barré syndrome
acute ischemic stroke
intravenous immunoglobulin
diagnosis
case report
title Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
title_full Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
title_fullStr Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
title_full_unstemmed Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
title_short Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke
title_sort case report guillain barre syndrome following acute ischemic brainstem stroke
topic Guillain-Barré syndrome
acute ischemic stroke
intravenous immunoglobulin
diagnosis
case report
url https://www.frontiersin.org/articles/10.3389/fimmu.2024.1403561/full
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