Structure and transport mechanism of human riboflavin transporters

Structure and transport mechanism of human riboflavin transporters

Abstract Riboflavin (vitamin B2) is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which act as key cofactors of many enzymes, thus has essential roles in cell growth and functions. Animals cannot synthesize riboflavin in situ, the intake, distribution and metabo...

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Main Authors: Ke Wang, Huiwen Chen, Lili Cheng, Jun Zhao, Bo Huang, Di Wu, Xin He, Yumeng Zhou, Yaxuan Yuan, Feng Zhou, Juquan Jiang, Ligong Chen, Daohua Jiang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59255-7
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