TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins

TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins

Toll-like receptors (TLRs) play an important role in the recognition of viral particles and activation of the innate immune system, but their role in SARS-CoV-2 infection is still poorly characterized. In the present study, we investigated the role of Toll-like receptor 10 (TLR10) in modulating the...

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Bibliographic Details
Main Authors: Špela Knez, Mojca Narat, Jernej Ogorevc
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
Toll-like receptor 10
interferons
proinflammatory cytokines
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1490478/full
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