Stability of an HIV/AIDS Treatment Model with Different Stages

An HIV/AIDS treatment model with different stages is proposed in this paper. The stage of the HIV infection is divided into two stages, that is, HIV-positive in the asymptomatic stage of HIV infection and HIV-positive individuals in the pre-AIDS stage. The fact that some individuals with HIV-positiv...

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Main Authors: Hai-Feng Huo, Rui Chen
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2015/630503
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author Hai-Feng Huo
Rui Chen
author_facet Hai-Feng Huo
Rui Chen
author_sort Hai-Feng Huo
collection DOAJ
description An HIV/AIDS treatment model with different stages is proposed in this paper. The stage of the HIV infection is divided into two stages, that is, HIV-positive in the asymptomatic stage of HIV infection and HIV-positive individuals in the pre-AIDS stage. The fact that some individuals with HIV-positive individuals after the treatment can be transformed into the compartment of HIV-positive individuals in the asymptomatic stage of HIV infection, the compartment of HIV-positive individuals in the pre-AIDS stage, or the compartment of individuals with full-blown AIDS is also considered. Mathematical analyses establish the idea that the global dynamics of the HIV/AIDS model are determined by the basic reproduction number R0. The disease-free equilibrium is globally asymptotically stable if R0<1. The endemic equilibrium is globally asymptotically stable if R0>1 for a special case. Numerical simulations are also conducted to support the analytic results.
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publishDate 2015-01-01
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series Discrete Dynamics in Nature and Society
spelling doaj-art-9ee192ef5d96490d991ee34ff90922062025-02-03T05:46:18ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2015-01-01201510.1155/2015/630503630503Stability of an HIV/AIDS Treatment Model with Different StagesHai-Feng Huo0Rui Chen1Department of Applied Mathematics, Lanzhou University of Technology, Lanzhou, Gansu 730050, ChinaDepartment of Applied Mathematics, Lanzhou University of Technology, Lanzhou, Gansu 730050, ChinaAn HIV/AIDS treatment model with different stages is proposed in this paper. The stage of the HIV infection is divided into two stages, that is, HIV-positive in the asymptomatic stage of HIV infection and HIV-positive individuals in the pre-AIDS stage. The fact that some individuals with HIV-positive individuals after the treatment can be transformed into the compartment of HIV-positive individuals in the asymptomatic stage of HIV infection, the compartment of HIV-positive individuals in the pre-AIDS stage, or the compartment of individuals with full-blown AIDS is also considered. Mathematical analyses establish the idea that the global dynamics of the HIV/AIDS model are determined by the basic reproduction number R0. The disease-free equilibrium is globally asymptotically stable if R0<1. The endemic equilibrium is globally asymptotically stable if R0>1 for a special case. Numerical simulations are also conducted to support the analytic results.http://dx.doi.org/10.1155/2015/630503
spellingShingle Hai-Feng Huo
Rui Chen
Stability of an HIV/AIDS Treatment Model with Different Stages
Discrete Dynamics in Nature and Society
title Stability of an HIV/AIDS Treatment Model with Different Stages
title_full Stability of an HIV/AIDS Treatment Model with Different Stages
title_fullStr Stability of an HIV/AIDS Treatment Model with Different Stages
title_full_unstemmed Stability of an HIV/AIDS Treatment Model with Different Stages
title_short Stability of an HIV/AIDS Treatment Model with Different Stages
title_sort stability of an hiv aids treatment model with different stages
url http://dx.doi.org/10.1155/2015/630503
work_keys_str_mv AT haifenghuo stabilityofanhivaidstreatmentmodelwithdifferentstages
AT ruichen stabilityofanhivaidstreatmentmodelwithdifferentstages