Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation
To avoid immune rejection, allograft recipients require drug-based immunosuppression, which has significant toxicity. An emerging approach is adoptive transfer of immunoregulatory cells. While mature dendritic cells (DCs) present donor antigen to the immune system, triggering rejection, regulatory D...
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Main Author: | |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Journal of Transplantation |
Online Access: | http://dx.doi.org/10.1155/2013/761429 |
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