Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation

To avoid immune rejection, allograft recipients require drug-based immunosuppression, which has significant toxicity. An emerging approach is adoptive transfer of immunoregulatory cells. While mature dendritic cells (DCs) present donor antigen to the immune system, triggering rejection, regulatory D...

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Bibliographic Details
Main Author: Giuseppe Vassalli
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2013/761429
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