Pharmacodynamic approaches to the use of mucoactive drugs
Cough is a reflex, protective and adaptive reaction of the body aimed at removing foreign sub-stances and/or pathologically altered tracheobronchial secretions from the respiratory tract. Cough is one of the most important components of pulmonary clearance, which is activated when natural mechanisms...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/197 |
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| author | S. V. Okovity A. A. Zaitsev N. A. Anisimova |
| author_facet | S. V. Okovity A. A. Zaitsev N. A. Anisimova |
| author_sort | S. V. Okovity |
| collection | DOAJ |
| description | Cough is a reflex, protective and adaptive reaction of the body aimed at removing foreign sub-stances and/or pathologically altered tracheobronchial secretions from the respiratory tract. Cough is one of the most important components of pulmonary clearance, which is activated when natural mechanisms fail. It can have both a positive value (clearing the airways) and a negative value (it tires the patient, disrupts sleep, nutrition, and can lead to various complica-tions). Therefore, the treatment of cough using pharmacological and nonmedicinal methods can reduce it in the case of excessive severity and improve pulmonary clearance. The basis of cough pharmacotherapy is mucoactive drugs, which form four pharmacological groups: expectorants, mucolytics, mucokinetics, mucoregulators. In addition, in some cases, drugs can be used to suppress the cough reflex in the central or peripheral link. All of them provide symptomatic cough relief and reduce the duration of symptoms. The choice of medicines for the treatment of cough is determined by their pharmacodynamics and features of influence on the nature of bronchial secretions. |
| format | Article |
| id | doaj-art-9eae4ae98a8f4c64a8b201494d8f2a9d |
| institution | DOAJ |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-9eae4ae98a8f4c64a8b201494d8f2a9d2025-08-20T03:20:17ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0101061010.26295/OS.2020.62.62.001196Pharmacodynamic approaches to the use of mucoactive drugsS. V. Okovity0A. A. Zaitsev1N. A. Anisimova2Saint-Petersburg Chemical Pharmaceutical UniversityN. N. Burdenko Military Clinical HospitalSaint-Petersburg Chemical Pharmaceutical UniversityCough is a reflex, protective and adaptive reaction of the body aimed at removing foreign sub-stances and/or pathologically altered tracheobronchial secretions from the respiratory tract. Cough is one of the most important components of pulmonary clearance, which is activated when natural mechanisms fail. It can have both a positive value (clearing the airways) and a negative value (it tires the patient, disrupts sleep, nutrition, and can lead to various complica-tions). Therefore, the treatment of cough using pharmacological and nonmedicinal methods can reduce it in the case of excessive severity and improve pulmonary clearance. The basis of cough pharmacotherapy is mucoactive drugs, which form four pharmacological groups: expectorants, mucolytics, mucokinetics, mucoregulators. In addition, in some cases, drugs can be used to suppress the cough reflex in the central or peripheral link. All of them provide symptomatic cough relief and reduce the duration of symptoms. The choice of medicines for the treatment of cough is determined by their pharmacodynamics and features of influence on the nature of bronchial secretions.https://journal.lvrach.ru/jour/article/view/197coughcough managingmucolyticsmucokineticsmucoregulatorsexpectorants |
| spellingShingle | S. V. Okovity A. A. Zaitsev N. A. Anisimova Pharmacodynamic approaches to the use of mucoactive drugs Лечащий Врач cough cough managing mucolytics mucokinetics mucoregulators expectorants |
| title | Pharmacodynamic approaches to the use of mucoactive drugs |
| title_full | Pharmacodynamic approaches to the use of mucoactive drugs |
| title_fullStr | Pharmacodynamic approaches to the use of mucoactive drugs |
| title_full_unstemmed | Pharmacodynamic approaches to the use of mucoactive drugs |
| title_short | Pharmacodynamic approaches to the use of mucoactive drugs |
| title_sort | pharmacodynamic approaches to the use of mucoactive drugs |
| topic | cough cough managing mucolytics mucokinetics mucoregulators expectorants |
| url | https://journal.lvrach.ru/jour/article/view/197 |
| work_keys_str_mv | AT svokovity pharmacodynamicapproachestotheuseofmucoactivedrugs AT aazaitsev pharmacodynamicapproachestotheuseofmucoactivedrugs AT naanisimova pharmacodynamicapproachestotheuseofmucoactivedrugs |