Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition
Cognitive dysfunction is a well-documented feature of schizophrenia (SZ) and bipolar (BD) disorder. The person's subjective experience of cognitive difficulties is less investigated. Here we investigated subjective cognition in SZ and BD compared to healthy controls (HC).Subjective and objectiv...
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Elsevier
2025-06-01
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| Series: | Schizophrenia Research: Cognition |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001325000022 |
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| author | Kristoffer Grimstad Håkon Sørensen Anja Vaskinn Christine Mohn Stine Holmstul Olsen Ole A. Andreassen Trine Vik Lagerberg Ingrid Melle Merete Glenne Øie Torill Ueland Beathe Haatveit |
| author_facet | Kristoffer Grimstad Håkon Sørensen Anja Vaskinn Christine Mohn Stine Holmstul Olsen Ole A. Andreassen Trine Vik Lagerberg Ingrid Melle Merete Glenne Øie Torill Ueland Beathe Haatveit |
| author_sort | Kristoffer Grimstad |
| collection | DOAJ |
| description | Cognitive dysfunction is a well-documented feature of schizophrenia (SZ) and bipolar (BD) disorder. The person's subjective experience of cognitive difficulties is less investigated. Here we investigated subjective cognition in SZ and BD compared to healthy controls (HC).Subjective and objective cognition were assessed in 91 SZ participants, 55 BD participants and 55 HC, applying a novel measure of subjective cognition, the self-assessed cognitive complaints scale (SACCS) and a clinically relevant neuropsychological test battery. The psychometric properties of SACCS were investigated. The relationship between subjective and objective cognition, and subjective cognition and clinical variables were explored in SZ and BD.The SACCS showed adequate psychometric properties. Clinical groups reported significantly more cognitive complaints than HCs, without differences between SZ and BD. There were no significant associations between subjective and objective cognitive measures. There was a small trend association between subjective cognition and insight in SZ participants, and moderate sized associations between subjective cognition and general psychopathology and functioning in BD participants.Although SZ participants are more cognitively impaired than BD participants, the two groups report similar levels of subjective cognitive complaints, with no association between subjective and objective cognition. Our results suggest that the expression of subjective cognition is associated with different clinical factors in SZ and BD. |
| format | Article |
| id | doaj-art-9e9abec03b53467799203803f8763774 |
| institution | Kabale University |
| issn | 2215-0013 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj-art-9e9abec03b53467799203803f87637742025-02-04T04:10:26ZengElsevierSchizophrenia Research: Cognition2215-00132025-06-0140100345Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognitionKristoffer Grimstad0Håkon Sørensen1Anja Vaskinn2Christine Mohn3Stine Holmstul Olsen4Ole A. Andreassen5Trine Vik Lagerberg6Ingrid Melle7Merete Glenne Øie8Torill Ueland9Beathe Haatveit10Department of Neurology, Akershus University Hospital, Lørenskog, Norway; Corresponding author.Department of Neurology, Akershus University Hospital, Lørenskog, NorwayCenter for Research and Education in Forensic Psychiatry, Oslo University Hospital, Oslo, Norway; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayNational Centre for Suicide Research and Prevention, Institute of Clinical Medicine, University of Oslo, Oslo, NorwaySection for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, NorwayCentre for Precision Psychiatry, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Section for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo, NorwaySection for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, NorwaySection for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Adult Psychiatry Unit, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Psychology, University of Oslo, Oslo, Norway; Department of Research, Innlandet Hospital Trust, Brumunddal, NorwaySection for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Department of Psychology, University of Oslo, Oslo, NorwayCentre for Precision Psychiatry, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayCognitive dysfunction is a well-documented feature of schizophrenia (SZ) and bipolar (BD) disorder. The person's subjective experience of cognitive difficulties is less investigated. Here we investigated subjective cognition in SZ and BD compared to healthy controls (HC).Subjective and objective cognition were assessed in 91 SZ participants, 55 BD participants and 55 HC, applying a novel measure of subjective cognition, the self-assessed cognitive complaints scale (SACCS) and a clinically relevant neuropsychological test battery. The psychometric properties of SACCS were investigated. The relationship between subjective and objective cognition, and subjective cognition and clinical variables were explored in SZ and BD.The SACCS showed adequate psychometric properties. Clinical groups reported significantly more cognitive complaints than HCs, without differences between SZ and BD. There were no significant associations between subjective and objective cognitive measures. There was a small trend association between subjective cognition and insight in SZ participants, and moderate sized associations between subjective cognition and general psychopathology and functioning in BD participants.Although SZ participants are more cognitively impaired than BD participants, the two groups report similar levels of subjective cognitive complaints, with no association between subjective and objective cognition. Our results suggest that the expression of subjective cognition is associated with different clinical factors in SZ and BD.http://www.sciencedirect.com/science/article/pii/S2215001325000022NeurocognitionCognitive impairmentSubjective assessmentCognitive complaintsPsychotic disordersFunctioning |
| spellingShingle | Kristoffer Grimstad Håkon Sørensen Anja Vaskinn Christine Mohn Stine Holmstul Olsen Ole A. Andreassen Trine Vik Lagerberg Ingrid Melle Merete Glenne Øie Torill Ueland Beathe Haatveit Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition Schizophrenia Research: Cognition Neurocognition Cognitive impairment Subjective assessment Cognitive complaints Psychotic disorders Functioning |
| title | Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| title_full | Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| title_fullStr | Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| title_full_unstemmed | Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| title_short | Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| title_sort | subjective cognition in schizophrenia and bipolar disorder investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition |
| topic | Neurocognition Cognitive impairment Subjective assessment Cognitive complaints Psychotic disorders Functioning |
| url | http://www.sciencedirect.com/science/article/pii/S2215001325000022 |
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